| 朱立宇,李 超,文 刚,林 源,陶树清.骨科假体表面涂层技术现状[J].现代生物医学进展英文版,2019,19(8):1591-1595. |
| 骨科假体表面涂层技术现状 |
| Current Status of Orthopedic Prosthesis urface Coating Technology |
| Received:June 05, 2018 Revised:June 28, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.08.043 |
| 中文关键词: 骨科 假体涂层 骨整合 感染 抗菌治疗 |
| 英文关键词: Orthopaedics Implant coatings Osseointegration Infection Antimicrobial treatments |
| 基金项目:黑龙江省教育厅科学技术研究项目（12521315） |
| Author Name | Affiliation | E-mail | | ZHU Li-yu | Second Department of Orthopedics, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China | 444545103@qq.com | | LI Chao | Second Department of Orthopedics, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China | | | WEN Gang | Second Department of Orthopedics, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China | | | LIN Yuan | Second Department of Orthopedics, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China | | | TAO Shu-qing | Second Department of Orthopedics, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, China | |
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| 中文摘要: |
| 摘要：由植入物界面处的相互作用可能引起无菌性松动和假体周围感染。而无菌性松动和假体周围感染仍然是一个难以治疗的问题，并且最终可能导致假体植入失败，引起严重后果。理想的植入物应能促进骨整合，防止细菌粘附，减少细菌感染。骨科植入技术主要基于生物材料的开发和使用，随着材料科学和细胞生物学的发展，已可以用新的植入物表面涂层的进展来解决这些问题。本文回顾总结了时下骨科常见的假体涂层设计和相关问题，以期为进一步研究提供借鉴。 |
| 英文摘要: |
| ABSTRACT: Interactions at the implant interface may cause aseptic loosening and infection around the prosthesis. Aseptic loosening and peri-prosthetic infection remain a difficult problem to treat, and may ultimately lead to implant failure and cause serious consequences. The ideal implant should be able to promote osseointegration, prevent bacterial adhesion and reduce bacterial infections. Orthopedic implanting techniques are primarily based on the development and use of biomaterials that, with advances in materials science and cell biology, have made it possible to address these issues with advances in new implant surface coatings. This review summarizes the current orthopedic prosthesis coating design and related issues in order to provide a reference for further research. |
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