| 吴家辉,郑宗志,高晓哲,吴晓萍,夏美玲.针灸联合康复理疗对急性脑梗死患者脑部血流供应及炎性因子的影响[J].现代生物医学进展英文版,2019,19(8):1508-1512. |
| 针灸联合康复理疗对急性脑梗死患者脑部血流供应及炎性因子的影响 |
| Effects of Acupuncture and Moxibustion Combined with Rehabilitation Physiotherapy on Cerebral Blood Flow Supply and Inflammatory Factors in Patients with Acute Cerebral Infarction |
| Received:November 17, 2018 Revised:December 12, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.08.024 |
| 中文关键词: 针灸 康复理疗 急性脑梗死 脑部血流供应 炎性因子 |
| 英文关键词: Acupuncture and moxibustion Rehabilitation physiotherapy Acute cerebral infarction Cerebral blood flow supply Inflammatory factors |
| 基金项目:南京军区医学科技资助项目（2013MS0299） |
| Author Name | Affiliation | E-mail | | WU Jia-hui | Department of Rehabilitation Medicine, The 910st Hospital of the PLA Joint Logistics Support Force, Quanzhou, Fujian, 362000, China | huihui_8606@sohu.com | | ZHENG Zong-zhi | Department of Rehabilitation Medicine, The 910st Hospital of the PLA Joint Logistics Support Force, Quanzhou, Fujian, 362000, China | | | GAO Xiao-zhe | Department of Rehabilitation Medicine, The 910st Hospital of the PLA Joint Logistics Support Force, Quanzhou, Fujian, 362000, China | | | WU Xiao-ping | Department of Rehabilitation Medicine, The 910st Hospital of the PLA Joint Logistics Support Force, Quanzhou, Fujian, 362000, China | | | XIA Mei-ling | Department of Rehabilitation Medicine, The 910st Hospital of the PLA Joint Logistics Support Force, Quanzhou, Fujian, 362000, China | |
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| 中文摘要: |
| 摘要 目的：探讨针灸联合康复理疗对急性脑梗死（ACI）患者脑部血流供应及炎性因子的影响。方法：选取2017年1月~2018年8月期间我院收治的ACI患者63例，根据随机数字表法将患者分为对照组（n=31）和研究组（n=32），对照组在常规西医治疗基础上给予康复理疗治疗，研究组在对照组基础上结合针灸进行治疗，1周为1个疗程，两组均治疗4个疗程。比较两组患者治疗4个疗程后的临床疗效，治疗前、治疗4个疗程后的脑部血流供应指标、炎性因子指标以及Fugl-Meyer运动功能评分（FMA）、改良Barthel指数评分（MBI）、神经功能缺损评分（NIHSS）。结果：研究组治疗4个疗程后总有效率为78.13%（25/32），高于对照组的51.61%（16/31）（P<0.05）。两组患者治疗4个疗程后FMA、MBI均较治疗前升高，且研究组高于对照组（P<0.05），NIHSS较治疗前降低，且研究组低于对照组（P<0.05）。两组患者治疗4个疗程后平均血流量（Qm）、平均血流速度（Vm）均较治疗前升高，且研究组高于对照组（P<0.05），外周阻力（Rv）、动态阻力（DR）均较治疗前降低，且研究组低于对照组（P<0.05）。两组患者治疗4个疗程后血清白介素-6（IL-6）、超敏C反应蛋白（hs-CRP）、肿瘤坏死因子-α（TNF-α）水平均低于治疗前，且研究组较对照组降低（P<0.05）。结论：针灸联合康复理疗治疗ACI患者，效果明显，可有效改善患者运动功能、神经功能及脑部血流供应情况，降低机体炎性因子水平，提高日常生活能力，具有一定的临床应用价值。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of acupuncture and moxibustion combined with rehabilitation physiotherapy on cerebral blood flow and inflammatory factors in patients with acute cerebral infarction (ACI). Methods: A total of 63 patients with ACI, who were admitted to the 910st Hospital of the PLA Joint Logistics Support Force from January 2017 to August 2018, were selected and were randomly divided into control group (n=31) and research group (n=32). The control group was treated with rehabilitation physiotherapy on the basis of conventional Western medicine. The research group was treated with acupuncture and moxibustion on the basis of the control group's therapy. 1 week was a curative effect. Both groups were treated for 4 courses. The clinical efficacy of the two groups after 4 courses of treatment was compared. The cerebral blood flow supply index, inflammatory factor index, Fugl-Meyer motor function score (FMA), modified Barthel index score (MBI) and neurological deficit score (NIHSS) were compared before and after 4 courses of treatment. Results: The total effective rate of the research group was 78.13% (25/32) after 4 courses of treatment, which was significantly higher than that[51.61% (16/31)] of the control group (P<0.05). The FMA and MBI in both groups increased after 4 courses of treatment compared with those before treatment, the indexes in the research group were higher than those in the control group (P<0.05). The NIHSS was lower than that before treatment, and the index in the research group was lower than that in the control group (P<0.05). The mean blood flow (Qm) and mean blood flow velocity (Vm) of the two groups after 4 courses of treatment were higher than those before treatment, and the indexes in the research group were higher than those in the control group (P<0.05). The peripheral resistance (Rv) and dynamic resistance (DR) were lower than those before treatment, and the research group was lower than the control group (P<0.05). The levels of serum interleukin-6 (IL-6), high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-α (TNF-α) of the two groups after 4 courses of treatment were all lower than those before treatment, the research group was lower than the control group(P<0.05). Conclusion: Acupuncture and moxibustion combined with rehabilitation physiotherapy is effective in treating ACI patients. It can effectively improve the motor function, nerve function and cerebral blood flow supply of patients, reduce the level of inflammatory factors, and improve daily living ability. It has certain clinical application value. |
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