| 王春亚,赵玉杰,王小闯,侯艳丽,王海涛.有创无创序贯通气对急性呼吸衰竭患者血糖水平及预后的影响[J].现代生物医学进展英文版,2019,19(8):1490-1493. |
| 有创无创序贯通气对急性呼吸衰竭患者血糖水平及预后的影响 |
| Effect of Sequential Invasive and Non-invasive Ventilation on Blood Glucose Level and Prognosis in Patients with Acute Respiratory Failure |
| Received:July 10, 2018 Revised:July 31, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.08.020 |
| 中文关键词: 有创无创序贯通气 急性呼吸衰竭 血糖 预后 |
| 英文关键词: Sequential Invasive and Non-invasive Ventilation Acute Respiratory Failure Blood Glucose Prognosis |
| 基金项目:陕西省科技攻关项目（2015SF-144） |
| Author Name | Affiliation | E-mail | | WANG Chun-ya | Department of ICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China | wangchunya_197604@163.com | | ZHAO Yu-jie | Department of ICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China | | | WANG Xiao-chuang | Department of ICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China | | | HOU Yan-li | Department of ICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China | | | WANG Hai-tao | Department of pharmacy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710004, China | |
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| 中文摘要: |
| 摘要 目的：探讨有创无创序贯通气和有创机械通气对急性呼吸衰竭患者血糖水平及预后的影响。方法：选取我院重症医学科2012年3月至2017年10月收治的急性呼吸衰竭患者81例，按照通气方式不同分为两组，对照组(41例)采用单纯有创机械通气治疗，观察组(40例)采用有创-无创序贯通气治疗。比较两组患者的血糖水平、临床指标、治疗时间和临床转归情况。结果：两组患者治疗后血糖水平均较治疗前显著升高(P<0.05)，而观察组血糖水平显著低于对照组(P<0.05)；对照组拔管时和观察组通气3h后患者的动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)、收缩压(SBP)和心率(HR)对比无显著性差异(P＞0.05)；观察组的通气时间、住院时间与对照组相比均较短(P<0.05)，撤机成功率高于对照组(P<0.05)，再插管率、呼吸机相关肺炎(VAP)和死亡率均显著低于对照组(P<0.05)。结论：有创无创序贯通气急性呼吸衰竭患者血糖水平较低，治疗时间较短，且再插管率、VAP和死亡率较小，显著改善患者预后。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effect of sequential invasive and non-invasive ventilation on blood glucose level and prognosis in patients with acute respiratory failure. Methods: 81 cases of patients with acute respiratory failure form March 2012 to October 2017 were selected, and divided into two groups according to the ventilation way, the control group (41 cases) using pure invasive mechanical ventilation treatment, observation group (40 cases) using sequential invasive and non-invasiveventilation treatment. The blood glucose levels, clinical indicators, treatment time and clinical outcomes were compared between the two groups. Results: Blood glucose levels were significant rise after treatment in both groups (P<0.05), blood glucose level was significantly lower in observation group than control group (P<0.05); there were no significantly difference of PaCO2, PaO2, SBP and HR between two groups (P＞0.05); ventilation time and hospitalization time in observation group was significantly shorter than the control group (P<0.05), the ventilator success rate in observation group was 82.50%, significantly higher than that of control group 53.66% (P<0.05), reintubation rate, VAPand mortality were significantly in observation group was significantly lower than the control group (P<0.05). Conclusion: There was a low blood glucose level, shorter treatment time, and a smaller reintubation rate, VAP and mortality used sequential invasive and non-invasiveventilation in the patients with acute respiratory failure, and significantly improved the prognosis of patients. |
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