| 沈英豪,张俊峰,张 欣,周 静,刘天骄.红细胞体积分布宽度对心力衰竭患者病情及预后转归的评估价值[J].现代生物医学进展英文版,2019,19(6):1060-1063. |
| 红细胞体积分布宽度对心力衰竭患者病情及预后转归的评估价值 |
| Evaluation Value of Red Blood Cell Distribution Width on the Severity and Prognosis of Patients with Heart Failure |
| Received:September 01, 2018 Revised:September 20, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.06.012 |
| 中文关键词: 心力衰竭 红细胞体积分布宽度 病情 预后 |
| 英文关键词: Heart failure Red blood cell distribution width Severity Prognosis |
| 基金项目:国家自然科学基金项目(81670316) |
| Author Name | Affiliation | E-mail | | SHEN Ying-hao | Department of Cardiology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai， 201999, China | siler610@163.com | | ZHANG Jun-feng | Department of Cardiology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai， 201999, China | | | ZHANG Xin | Department of Cardiology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai， 201999, China | | | ZHOU Jing | Department of Cardiology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai， 201999, China | | | LIU Tian-jiao | Department of Cardiology, The Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai， 201999, China | |
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| 中文摘要: |
| 摘要 目的：研究红细胞体积分布宽度(RDW)对心力衰竭患者病情及预后转归的评估价值。方法：将我院心内科收治的110例心力衰竭患者(研究组)根据病情分为NYHA Ⅱ级30例、Ⅲ级46例、Ⅳ级34例，另选择同期健康体检者110例作为对照组。同时根据患者6个月内预后情况分为存活组(91例)和死亡组(19例)。比较分析各组患者RDW水平、死亡率，采用单因素和多因素logistic回归分析心力衰竭预后的影响因素。结果：研究组中，NYHA Ⅲ~Ⅳ级患者RDW水平明显高于对照组，且随着NYHA分级的增加，RDW水平明显升高(P<0.05)。NYHA Ⅳ级患者死亡率明显高于NYHA Ⅱ、Ⅲ级患者(P<0.05)。与死亡组比较，存活组年龄明显较小，入院时Hcy、CRP、GLU、RDW、NT-pro BNP明显降低，Hb、RBC、LVEF水平明显升高(P <0.05)。年龄、入院时NT-pro BNP和RDW是心力衰竭的独立危险因素，而LVEF水平是独立保护因素(P<0.05)。结论：RDW可反映心力衰竭患者的病情严重程度，对于预后转归评估具有重要指导意义。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the evaluation value of red blood cell distribution width(RDW) on severity and prognosis of patients with heart failure. Methods: According to the severity of disease, 110 cases of heart failure patients(research group) who admitted in the department of cardiology of our hospital were divided into different grades, including 30 patients of NYHA Ⅱ, 46 patients of NYHA Ⅲ, 34 patients of NYHA Ⅳ. At the same time, 110 cases of physical examination were selected as the control group. All the patients were also divided into the survival group(n=91) and the death group (n=19) according to the prognosis within 6 months. The RDW and mortality were compared among the groups, univariate analysis and multivariate logistic analysis were performed to assess the influencing factors of heart failure. Results: The RDW level in NYHA Ⅲ~Ⅳ of research group were significantly lower than that of the control group, and with the increase of NYHA classification, the RDW level was significantly increased (P<0.05). Compared with the death group, the age in survival group was obviously younger, the levels of Hcy, CRP, GLU, RDW, NT-pro BNP on admission were significantly decreased, the LVEF level was significantly increased(P<0.05). Logistic regression analysis showed that age, NT-pro BNP, RDW on admission were independent risk factors of heart failure, and LVEF was independent protection factor(P<0.05). Conclusion: RDW can reflect the severity of heart failure, it has important guiding meaning for the prognosis evaluation of patients with heart failure. |
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