| 朱 佳,延 芳,王婷婷,于碧磬,左 静,姬佳妮.营养支持用于急性发作期慢性阻塞性肺疾病的效果研究[J].现代生物医学进展英文版,2019,19(5):899-902. |
| 营养支持用于急性发作期慢性阻塞性肺疾病的效果研究 |
| Effect of Nutrition Support on the Chronic Obstructive Pulmonary Disease in Acute Episode |
| Received:October 11, 2018 Revised:November 21, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.05.023 |
| 中文关键词: 慢性阻塞性肺疾病 营养支持 肺功能指标 血气指标 |
| 英文关键词: Chronic obstructive pulmonary disease Nutrition support Lung function index Nutrition index |
| 基金项目:国家自然科学基金项目(81660140) |
| Author Name | Affiliation | E-mail | | ZHU Jia | People's hospital of xinjiang uygur autonomous region is the third ward, Urumqi, Xinjiang, 830000, China | 63672728g@qq.com | | YAN Fang | Nutrition department of the first affiliated hospital of shihezi university in Xinjiang, Shihezi, Xinjiang, 832002, China | | | WANG Ting-ting | Health Management, Shanghai University of Medicine Health Science, Shanghai, 201318, China | | | YU Bi-qing | Department of respiration Wuhan central hospital, Wuhan, Hubei, 430000, China | | | ZUO Jing | People's hospital of xinjiang uygur autonomous region is the third ward, Urumqi, Xinjiang, 830000, China | | | JI Jia-ni | People's hospital of xinjiang uygur autonomous region is the third ward, Urumqi, Xinjiang, 830000, China | |
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| 中文摘要: |
| 摘要 目的：探讨营养支持用于急性发作期慢性阻塞性肺疾病患者的临床效果。方法：选取2015年1月至2017年1月经新疆维吾尔自治区人民医院诊断的160例急性发作期慢性阻塞性肺疾病患者，随机分为两组，每组各80例。对照组仅给予抗炎、解痉、平喘等治疗；观察组在此基础上加以营养支持治疗。检测和比较两组治疗前后的肺功能指标、营养状况、血气指标、免疫指标、住院时间。结果：治疗后，观察组的肺功能指标第一秒用力呼气量(FEV)、第一秒用力呼气量与用力肺活量的百分比(FEV1%)、营养状况指标(血清白蛋白(ALB)、前白蛋白(PALB)、免疫功能指标(CD3+、CD4+、CD4+/CD8+)水平及外周淋巴细胞计数均较照组显著升高(P<0.05)。此外，观察组的PO2高于对照组，PCO2较对照组降低，且住院时间均明显短于对照组(P<0.05)。结论：及时进行营养支持治疗有助于改善急性发作期慢性阻塞性肺疾病患者的肺功能及免疫功能，并缩短住院时间。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical effect of nutritional support on the Chronic Obstructive Pulmonary Disease in Acute Episode. Methods: A total of 160 cases of chronic obstructive pulmonary disease diagnosed in the people's hospital of xinjiang au- tonomous region were selected from January 2015 to January 2017. They were randomly divided into two groups, 80 cases in each groups. The control group was only treated with anti-infection and antispasmodic asthma. The observation group is based on the nutrition support treatment. The lung function index, nutrition index, blood gas index and hospitalization time were measured and compared be- fore and after treatment in the two groups. Results: There was significant difference in lung function index(FEV1%), nutrition index(ALB, PALB), immune function indexes(CD3+, CD4+, CD4+/CD8+) and peripheral lymphocyte count before and after treatment in the ob- servation group(P<0.05), In addition, the PO2 of the observation group was higher than that of the control group, and PCO22 was lower than that of the control group. And the hospitalization time was significantly shorter than the control group (P<0.05). Conclusion: Timely nutritional support therapy can help improve the lung function and the immune function of patients with chronic obstructive pulmonary disease during acute attacks and shorten the length of hospital stay. |
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