| 孙亚召,黄淑田,高旭苗,王玲霞,葛婕丽,姚滨琪.急性冠脉综合征患者NLR、MPV与Gensini评分的相关性分析[J].现代生物医学进展英文版,2019,19(3):548-551. |
| 急性冠脉综合征患者NLR、MPV与Gensini评分的相关性分析 |
| Analysis of the correlation of NLR and MPV with Gensini Score in Patients with Acute Coronary Syndrome |
| Received:June 28, 2018 Revised:July 23, 2018 |
| DOI：10.13241/j.cnki.pmb.2019.03.035 |
| 中文关键词: 急性冠脉综合征 平均血小板体积 中性粒细胞/淋巴细胞 Gensini评分 |
| 英文关键词: Acute coronary syndrome Average platelet volume Neutrophils/lymphocytes Gensini score |
| 基金项目: |
| Author Name | Affiliation | E-mail | | SUN Ya-zhao | Shanxi Medical University, Taiyuan, Shanxi, 030000, China | sunyazhao@icloud.com | | HUANG Shu-tian | Department of Cardiology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030000, China | | | GAO Xu-miao | Shanxi Medical University, Taiyuan, Shanxi, 030000, China | | | WANG Ling-xia | Shanxi Medical University, Taiyuan, Shanxi, 030000, China | | | GE Jie-li | Shanxi Medical University, Taiyuan, Shanxi, 030000, China | | | YAO Bin-qi | Shanxi Medical University, Taiyuan, Shanxi, 030000, China | |
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| 中文摘要: |
| 摘要 目的：探讨急性冠脉综合征(Acute Coronary Syndrome，ACS)患者的中性粒细胞/淋巴细胞(Neutrophils/lymphocyte，NLR)、平均血小板体积(Mean platelet volume，MPV)与Gensini评分的相关性。方法：将156例ACS患者依据冠状动脉造影结果分为单支病变组、双支病变组及三支病变组，比较各组间NLR、MPV、Gensini评分及一般临床资料，并分析不同指标之间的相关性。结果：与双支病变组、单支病变组相比较，三支病变组吸烟、糖尿病、低密度脂蛋白胆固醇(low density lipoprotein cholesterol，LDL-C)、高密度脂蛋白胆固醇（high density lipoprotein cholesterol，HDL-C）、尿酸（uric acid，UA）、NLR、MPV、Gensini评分均显著升高(P<0.05)；与单支病变组相比较，双支病变组吸烟、糖尿病、LDL-C、HDL-C、UA、NLR、MPV、Gensini评分均显著升高(P<0.05)；三组间年龄、性别、高血压、总胆固醇（total cholesterol，TC）、甘油三酯（triglyceride，TG）、肌酐(creatinine，Cr)比较差异均无统计学意义(P>0.05)。Pearson相关性分析表明：NLR、MPV与Gensini评分均呈正相关(r=0.482、0.702, P<0.05)。结论：ACS患者MPV和NLR与冠状动脉病变程度呈显著正相关，可有效评估冠状动脉狭窄程度。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the correlation of neutrophils/lymphocyte (NLR), mean platelet volume (MPV) with gensini score in Acute coronary syndrome (ACS). Methods: 156 cases of ACS patients were divided into three groups according to the results of coronary angiography: single lesion group, double branch lesions, tripathic group. The NLR, MPV, Gensini score and general clinical data were compared between different groups and the correlation of different index were analyzed. Results: Compared with the single vessel lesion group and double branch lesion group, the percentage of patients with smoking and diabetes, the serum LDL-C、HDL-C, UA, NLR, MPV and Gensini score were significantly increased in the three branches of lesion group(P<0.05); Compared with single vessel lesion group, the above index were significantly increased in he double branch lesion group (P<0.05). There was no significant difference in the age, gender, percentage of patients with hypertension, TC, TG and Cr between the three groups (P>0.05). The Pearson correlation analysis showed that NLR and MPV were positively correlated with Gensini score (r=0.482, 0.702, P<0.05). Conclusion: The MPV and NLR were significantly positive correlated with the degree of coronary artery disease in patients with ACS, and they can effectively assess the degree of coronary artery stenosis. |
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