| 章 锐,田 瑶,KUSH,沈文状,李兴睿,朱 智.甲状腺乳头状癌淋巴结转移的临床危险因素分析[J].现代生物医学进展英文版,2018,(24):4764-4767. |
| 甲状腺乳头状癌淋巴结转移的临床危险因素分析 |
| Clinical Risk Factors of Lymph Node Metastasis in Papillary Thyroid Carcinoma |
| Received:June 06, 2018 Revised:June 30, 2018 |
| DOI：10.13241/j.cnki.pmb.2018.24.037 |
| 中文关键词: 甲状腺乳头状癌 癌结节大小 淋巴结转移 |
| 英文关键词: Papillary thyroid carcinoma Tumor size Lymph node metastasis |
| 基金项目: |
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| 中文摘要: |
| 摘要 目的：探讨甲状腺乳头状癌发生颈部淋巴结转移的危险因素。方法：回顾性分析我院自2017年1月至2017年5月手术治疗甲状腺乳头状癌病人177例的临床资料，采用卡方检验、t检验及logistic回归分析甲状腺乳头状癌发生颈部淋巴结的危险因素。结果：甲状腺乳头状癌淋巴结转移率为45.8 %，术后并发症发生率为6.2 %，淋巴结转移组较未转移组年龄更小、癌结节更大（P＜0.05），两组比较性别无统计学差异（P＞0.05），0.5 cm＜癌结节≤1 cm组较癌结节≤0.5 cm组更易出现淋巴结转移（P＜0.05），年龄大于45岁、癌结节≤0.5 cm的患者，9.6 %发生淋巴结转移。Logistic回归分析提示年龄、癌结节大小是淋巴结转移的独立危险因素（P＜0.05）。结论：年龄、癌结节大小是淋巴结转移的独立危险因素，年龄越小、癌结节越大的甲状腺乳头状癌患者，越容易出现颈部淋巴结转移。 |
| 英文摘要: |
| ABSTRACT Objective: To determine the risk factors of neck lymph node metastasis in papillary thyroid carcinoma(PTC). Methods: The clinical and pathologic data of 177 cases of patients who were first diagnosed as PTC in the Huazhong University of Science and Technology affiliated Tongji Hospital from January 2017 to May 2017 were retrospectively studied, Chi-square, t-test and logistic regres- sion analysis were used to identify the risk factors of neck lymph node metastasis. Results: 45.8 % of the patients appeared lymph node metastasis and the incidence of postoperative complications was 6.2 %. Patients with lymph node metastasis were younger and had big- ger tumor size than those without metastasis(P＜0.05). No statistical difference was found in the gender between the two groups(P＞0.05). Lymph node metastasis was more found in patients with 0.5 cm＜tumor size≤1 cm than thoe with tumor≤0.5 cm(P＜0.05). 9.6 % of the patients aged＞45 years and tumor size ≤0.5 cm appeared lymph node metastasis. Logistic regression analysis revealed age and tu- mor size were independently risk factors for the neck lymph node metastasis(P＜0.05). Conclusion: Age and tumor size were indepen- dently risk factors for the neck lymph node metastasis, the higher probability of lymph node metastasis was in the younger patients with bigger tumor size. |
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