| 孙 欣,田思萌,杨舒奇,黄凌佳,李 慧,黄明莉.干细胞在妇产科若干疾病中研究及应用[J].现代生物医学进展英文版,2018,(21):4198-4200. |
| 干细胞在妇产科若干疾病中研究及应用 |
| New Progress of Stem Cells in Several Diseases in Obstetrics and Gynecology |
| Received:March 06, 2018 Revised:March 31, 2018 |
| DOI：10.13241/j.cnki.pmb.2018.21.045 |
| 中文关键词: 干细胞 妇产科 子宫内膜疾病 宫内干细胞移植 妊娠期高血压疾病 生殖医学 |
| 英文关键词: Stem cell Obstetrics and gynecology Endometrium disease In utero stem cell transplantation Hypertensive disorder complicating pregnancy Reproductive medicine |
| 基金项目:国家自然科学基金青年基金项目（81401203） |
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| 中文摘要: |
| 摘要：干细胞是一类具有自我更新和增殖分化能力的细胞，按其发育阶段可分为胚胎干细胞（embryonic stem cell，ESC）和成体干细胞（adult stem cell，ASC）。由于干细胞这种特殊的增殖分化潜能，使其具备着多学科临床治疗的可塑性，研究意义巨大。随着子宫内膜干细胞的发现以及对其他类型干细胞提取手段的进步，干细胞为治疗子宫内膜相关性疾病带来了全新的思路。此外，宫内干细胞移植治疗胎儿疾病，干细胞介导损伤后血管内皮的修复以及改善生育功能、治疗不孕症等几个领域的研究也取得了显著的成果。本文参考近7年国内外文献，以干细胞治疗妇产科几种常见疾病的最新研究进展为主要内容进行综述。 |
| 英文摘要: |
| ABSTRACT: Stem cells have the ability to self renew and proliferate and differentiate, which can be divided into embryonic stem cells(ESC) and adult stem cells(ASC) according to their developmental stages. Stem cells have considerable plasticity in multidisciplinary clinical treatment because of the special potential, which is of great significance. With the discovery of endometrial stem cells and the progress of extraction methods, stem cells have brought new ideas for the treatment of endometrial related diseases. Besides, significant results have been achieved in several fields of research, such as in utero stem cell transplantation for the treatment of fetal diseases, plero- sis of injured vascular endothelial cells induced by stem cell, improvement of fertility function and treatment of infertility. This paper gave a review on the resent research of several common diseases in obstetrics and gynecology at home and abroad in the last 7 years. |
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