| 秦田雨,董笑克,孙 文,吴丽丽,秦灵灵,潘雅婧,宋紫临,张程斐,刘铜华.基因组学技术推动中医药精准医学研究现状分析与展望[J].现代生物医学进展英文版,2018,(13):2597-2600. |
| 基因组学技术推动中医药精准医学研究现状分析与展望 |
| Analysis on Current Research on Genomics Promoting Precision Medicine of Chinese Medicine and Prospects |
| Received:August 31, 2017 Revised:September 29, 2017 |
| DOI：10.13241/j.cnki.pmb.2018.13.042 |
| 中文关键词: 精准医学 中医药 基因组学 |
| 英文关键词: Precision medicine Chinese medicine Genomics |
| 基金项目:国家自然科学基金项目（81373587） |
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| 中文摘要: |
| 摘要：中医药具有精准医学的核心“个体化诊断和治疗”要素。基因组学技术在中医药基于体质的精准预防、个体化诊断与药物、针灸治疗、药物复杂性、包括中医药干预人体微生物环境等方面已经有较多应用。这与精准医学通过分析人群基因信息、生活方式、环境因素等了解疾病发生发展机制、针对相关靶点开发药物的方法及目标相匹配。未来将在整合各组学技术、结合中医药自身特色等方面应用于中医药精准医学研究，为实现中医药现代化及精准治疗的目标提供助力。 |
| 英文摘要: |
| ABSTRACT: Chinese medicine is equipped with the key factor of precision medicine, individualized diagnosis and treatment. Genomics have been widely applied in many aspects, including precision diagnosis based on constitution, individualized diagnosis, drug administration and acupuncture, research on the complexity of medicine, as well as Chinese medicine intervening microbe environment in human body. All of these are matched up with the method and object of precision medicine of learning about mechanism of occurrence and development of disease via analyzing group gene information, life style and environmental facotrs, and developing medicine focusing on related targets. In the future, more efforts will be collected on integrating each omic technology, taking the feature of Chinese medicine in to consideration, assisting achieving the goal of realizing Chinese medicine modernization and precision medicine. |
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