| 赵 霞,陈 召,王文胜,张鑫雨,李 哲,卢 强.非小细胞肺癌术后并发乳糜胸对患者生活质量影响的研究[J].现代生物医学进展英文版,2018,(13):2583-2587. |
| 非小细胞肺癌术后并发乳糜胸对患者生活质量影响的研究 |
| A Study on the Effect of Chylothorax on the Quality of Life of Non-small Cell Lung Cancer Patients after Operation |
| Received:January 09, 2018 Revised:February 03, 2018 |
| DOI：10.13241/j.cnki.pmb.2018.13.039 |
| 中文关键词: 非小细胞肺癌 乳糜胸 生活质量 |
| 英文关键词: Non-small cell lung cancer Chylothorax The quality of life |
| 基金项目:陕西省公关科技项目（2015SF028） |
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| 中文摘要: |
| 摘要 目的：探讨非小细胞肺癌术后并发乳糜胸对患者生活质量的影响。方法：采用生活质量测定量表(QLQ-C30)回顾性分析第四军医大学唐都医院胸外科自2013年至2016年中收治的1015例肺癌手术患者的生活质量，发生乳糜胸组记为A组，未发生乳糜胸组记为B组。对比术前和术后1、3、6和12个月的生活质量有无统计学差异。结果：①术后1月时，除了社会功能、便秘、腹泻以外，两组生活质量指标评分均显著低于术前，且B组均显著低于A组，有统计学差异(表3，P<0.05)。在手术后3月及以后逐渐恢复，至12月时，各组指标与术前基本相同(表3，P>0.05)；②两组术后生活质量相比较，术后1、3月，除社会功能、便秘、腹泻以外，其余生活质量功能指标B组均显著优于A组，有统计学差异(表3，P<0.05)。在手术后6月及以后，B组所有指标与A组无统计学差异(表3，P>0.05)。结论：肺癌根治术后发生乳糜胸患者生活质量显著低于未发生乳糜胸患者，因此应合理选择手术方式，注意术中操作，降低乳糜胸发生率，提高肺癌患者术后的生活质量。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of chylothorax on the quality of life of patients with non-small cell lung cancer after operation. Methods: 1015 patients which under lung cancer surgery in the Department of Thoracic Surgery of TangDu Hospital of Fourth Military Medical University from 2013 to 2016 were retrospectively analyzed with the quality of life scale core scale (QLQ C30). The patients with chylothorax notes for group A, the patients without chylothorax notes for group B. To analyze whether there have statistical differences of the quality of life before and at 1, 3, 6 and 12 months after surgery. Results: ①The postoperative quality of life was significantly lower than preoperative except for social function, constipation and diarrhea in the first month after operation, and there were statistically significant differences (table 3, P<0.05). The indexes were gradually recovered in the third month after operation and basically reach the same as before operation in the twelfth month after operation (table 3, P>0.05). ②The quality of life of group B were significantly superiorer to group A in addition to the social function, constipation and diarrhea in the first and third month after operation, and there were statistically significant differences (table 3, P<0.05). There was no statistical difference between the group B and group A in the sixth and twelfth month after surgery (table 3, P>0.05). Conclusion: The quality of life of non-small cell lung cancer patients with chylothorax were significantly lower than that without chylothorax after operation. Therefore, we should improve the quality of life of non-small cell lung cancer patients by selecting suitable surgical method, paying more attention on operation, reducing the incidence of chylothorax. |
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