| 王 鑫,夏 涵,李 斌,池叶楠,王秋育.罗哌卡因复合舒芬太尼持续硬膜外麻醉对无痛分娩镇痛效果及母婴状况的影响[J].现代生物医学进展英文版,2018,(7):1293-1296. |
| 罗哌卡因复合舒芬太尼持续硬膜外麻醉对无痛分娩镇痛效果及母婴状况的影响 |
| Effect of Continuous Epidural Anesthesia with Ropivacaine and Sufentanil on Analgesic Effect and Maternal and Infant Condition in Painless Labor |
| Received:October 04, 2017 Revised:October 27, 2017 |
| DOI：10.13241/j.cnki.pmb.2018.07.019 |
| 中文关键词: 分娩镇痛 舒芬太尼 罗哌卡因 硬膜外麻醉 镇痛效果 |
| 英文关键词: Labor analgesia Sufentanil Ropivacaine Epidural anesthesia Analgesia effect |
| 基金项目:北京市科委科技计划项目（SCW2012-104） |
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| 中文摘要: |
| 摘要 目的：探讨罗哌卡因复合舒芬太尼持续硬膜外麻醉对无痛分娩镇痛效果及母婴状况的影响。方法：选择我院产科2014年2月至2015年5月足月妊娠初产妇180例，按照随机数字表法分为治疗组（n=90）和对照组（n=90），治疗组采用4 ?滋g舒芬太尼复合3 mg罗哌卡因持续硬膜外麻醉进行分娩镇痛，对照组按阴道分娩常规处理，未用任何止痛措施。观察镇痛5 min、10 min、30 min、60 min时VAS评分，比较两组产妇的阴道出血量、产程、顺产率、剖宫产率，观察两组镇痛显效时间、镇痛时间、新生儿Apgar评分。结果：镇痛5 min，两组患者VAS评分无统计学差异（P>0.05），随着时间的推移，两组VAS评分逐渐降低，与对照组相比，治疗组在镇痛后10 min、30 min及60 min时VAS评分均明显降低，差异有统计学意义（P<0.05）。治疗组产妇镇痛显效时间、阴道出血量明显低于对照组（P<0.05），两组产程、镇痛时间、新生儿Apgar评分差异无统计学意义（P>0.05）。治疗组的顺产率和剖宫产率与对照组比较，治疗组产妇的顺产率提高，差异均有统计学意义（P<0.05）。结论：罗哌卡因复合舒芬太尼持续硬膜外麻醉镇痛对于无痛分娩镇痛效果较好，减轻疼痛，减少出血量，安全性高，值得临床推广。 |
| 英文摘要: |
| ABSTRACT Objective: To study the effect of continuous epidural anesthesia with ropivacaine and sufentanil on analgesic effect and maternal and infant condition in painless labor. Methods: 180 full term pregnant women, who were admitted to Dongfang Hospital from February 2014 to May 2015, were selected and randomly divided into treatment group (n=90) and control group (n=90). The treatment group was given 4 μg of sufentanil combined with 3mg ropivacaine for epidural analgesia, while the control group was given routine vaginal delivery without any pain relief measures. The VAS scores at analgesia 5 min, 10 min, 30 min and 60 min were observed. The vaginal bleeding, duration of labor, delivery rate and cesarean section rate were compared between the two groups. The analgesic effec- tive time, analgesic time and Apgar scores of the newborns were observed between the two groups. Results: At analgesia 5 min, there was no significant difference in the VAS scores between the two groups (P>0.05). As time went on, the VAS scores in the two groups de- creased gradually. Compared with the control group, the VAS scores in the treatment group were significantly lower at analgesia 10 min, 30 min and 60 min, the differences were statistically significant (P<0.05). The effective time and the amount of vaginal bleeding in the treatment group were significantly lower than those in the control group (P<0.05). There were no significant differences in the duration of labor,the time of analgesia and the Apgar scores of newborns between the two groups (P>0.05). Compared with the control group, the de- livery rate in the treatment group was higher,the differences were statistically significant (P<0.05). Conclusion: Ropivacaine and sufen- tanil with continuous epidural analgesia for epidural analgesia has obviously analgesic effect and can reduce the pain and the amount of bleeding, with high safety, which is worthy of clinical promotion. |
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