| 潘 磊,沈宏一,郑伶俐,蔡东成,高 旭.口腔种植修复与常规修复对牙列缺失患者生活质量及龈沟液细胞因子水平的影响[J].现代生物医学进展英文版,2018,(6):1141-1145. |
| 口腔种植修复与常规修复对牙列缺失患者生活质量及龈沟液细胞因子水平的影响 |
| Effect of Oral Implant Repair and Routine Repair on Quality of Life and Levels of Cell Factors in Gingival Crevicular Fluid in Patients with Missing Dentition |
| Received:October 01, 2017 Revised:October 23, 2017 |
| DOI：10.13241/j.cnki.pmb.2018.06.030 |
| 中文关键词: 口腔种植修复 常规修复 牙列缺失 生活质量 龈沟液 细胞因子 |
| 英文关键词: Oral implant repair Routine repair Missing dentition Quality of life Gingival crevicular fluid Cell factor |
| 基金项目:上海市卫计委面上项目(201485) |
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| 中文摘要: |
| 摘要 目的：研究口腔种植修复与常规修复对牙列缺失患者生活质量及龈沟液细胞因子水平的影响。方法：选择从2015年7月到2016年7月在我院接受治疗的牙列缺失患者108例作为研究对象。根据随机数字表法将患者分为对照组（n=54）和观察组（n=54），对照组实施常规修复，观察组给予口腔种植修复，随访3个月后，对比两组患者疗效、生活质量、治疗前及治疗3个月后龈沟液的细胞因子水平变化以及并发症情况。结果：观察组的总有效率较对照组明显升高（98.15%vs87.04%）（P<0.05）。治疗后3个月两组的生理功能、情感功能以及社会功能评分均分别较治疗前升高，且观察组高于对照组（P<0.05）。治疗后3个月两组患者的白细胞介素-6（IL-6）、白细胞介素-8（IL-8）以及肿瘤坏死因子-α（TNF-α）水平均分别高于治疗前，而观察组低于对照组（P<0.05）。观察组患者并发症的总发生率较对照组明显降低（7.41%vs22.22%）（P<0.05）。结论：牙列缺失患者经口腔种植修复方式治疗的效果更好，对于龈沟液细胞因子水平上升具有明显的抑制作用，减少并发症，值得关注及推广。 |
| 英文摘要: |
| ABSTRACT Objective: To study the effect of oral implant repair and routine repair on the quality of life and the levels of cell factors in gingival crevicular fluid in patients with missing dentition. Methods: A total of 108 patients with missing dentition, who were treated in 85th Hospital of People's Liberation Army from July 2015 to July 2016, were selected and randomly divided into control group (n=54) and observation group (n=54). The control group was received routine repair, and the observation group was given oral implant repair. After 3 months of follow-up, the efficacy, quality of life, levels of cell factors in gingival crevicular fluid before treatment and 3 months after treatment and complications were compared between the two groups. Results: The total effective rate of the observation group was significantly higher than that of the control group (98.15% vs 87.04%) (P<0.05). 3 months after treatment, the scores of physiological function,emotional function and social function of the two groups were higher than those before treatment, and the observation group was higher than the control group (P<0.05); the levels of interleukin-6 (IL-6), interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α) in the two groups were all higher than those before treatment, while those in the observation group were lower than those in the control group (P<0.05); the total incidence of complications in the observation group was significantly lower than that in the control group (7.41%vs22.22%) (P<0.05). Conclusion: The effect of oral implant repair is better in the patients with missing dentition, and it has obvious inhibitory effect on the rise of cell factors in gingival crevicular fluid and can reduce complications, which is worthy of attention and promotion. |
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