| 丁 博,卢燕鸣,李亚琴,徐凌云,李小燕,于 清.血乳酸在婴幼儿喘息性疾病中的临床意义[J].现代生物医学进展英文版,2018,(2):264-267. |
| 血乳酸在婴幼儿喘息性疾病中的临床意义 |
| Clinical Significance of Blood Lactate in the Infants with Asthmatic Disease |
| Received:September 04, 2017 Revised:September 26, 2017 |
| DOI：10.13241/j.cnki.pmb.2018.02.015 |
| 中文关键词: 乳酸 婴幼儿 喘息 |
| 英文关键词: Lactate Infant Asthmatic |
| 基金项目:上海申康医院发展中心郊区三级医院临床能力建设项目(SHDC12014905) |
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| 中文摘要: |
| 摘要 目的：探讨血乳酸在婴幼儿喘息性疾病中的临床意义。方法：随机选取我院2014年9月至2015年4月收治的5岁以内的支气管肺炎患儿245例，分为喘息组及非喘息组，比较其血乳酸水平。喘息组花儿根据年龄分为：A(≤12月)、B(12月＜年龄≤36月)及C(36月＜年龄≤60月)组，乳酸正常组(＜2.2 mmol/L)及乳酸升高组(≥2.2 mmol/L)，比较其发病年龄、激素治疗量、治疗天数及住院费用差异。结果：与非喘息组比较，喘息组血乳酸值显著升高，且喘息组2.2 mmol/L≤Lac＜4.4 mmol/L患儿比例显著高于非喘息组(P＜0.05)。不同年龄亚组患儿的血乳酸值比较差异均具有统计学意义，年龄越小，乳酸值越高(P＜0.05)。与乳酸正常组比较，乳酸升高组患儿年龄小(P＜0.05)，激素治疗量高(P＜0.05)，但两组住院天数及治疗费用比较并无统计学差异(P＞0.05)。结论：喘息性疾病患儿年龄越小，血乳酸值明显升高，血乳酸值与喘息患儿激素治疗量有一定关系，故在指导婴幼儿喘息性疾病激素的合理应用及病情评估中有一定的参考意义。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical significance of blood lactate in the infants with asthmatic disease. Methods: From September 2014 to April 2015, 245 cases of infants diagnosed with bronchopneumonia were enrolled and divided into the asthmatic group and the non-asthmatic group. The asthmatic group was divided into A（≤12 month）, B(12 month＜age ≤36 month）, C(36 month＜age ≤60 month） according to the age. Asthmatic patients were then divided into the normal lactate group（＜2.2 mmol/L) and increased lactate group（≥2.2 mmol/L）. The level of blood lactate, age of onset, the therapeutic dose of glucocorticoid, days of treatment and hospitalization expenses were compared between two groups. Results: The blood lactate in sthmatic patients was obviously higher than that of the non-asthmatic patients(P＜0.05). The proportion of children in the sthmatic group with lactate level between 2.2 mmol/L and 4.4 mmol/L is more than non-asthmatic group(P＜0.05). The blood lactate of children with different age in the asthmatic group is significantly different. The smaller age with higher blood lactate level. Compared with normal lactate group, the age of increased lactate group was younger(P＜0.05), the therapeutic dose of glucocorticoid was higher(P＜0.05). But there was no significant difference in the hospital stay and hospitalization expenses(P＜0.05). Conclusion: The blood lactate was obviously increased in the infants with wheeze or with younger age. It had certain relation with the therapeutic dose of glucocorticoid used in asthmatic infants. Which made a significance in guiding the rational use of glucocorticoid in infants with asthmatic diseases. |
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