| 章 燕,祝亚平,鲍 伟,刘银萍,卢君君.前哨淋巴结检测方法及其在肿瘤中的研究进展[J].现代生物医学进展英文版,2018,(1):164-167. |
| 前哨淋巴结检测方法及其在肿瘤中的研究进展 |
| Sentinel Lymph Node Detection and Its Progress in Tumors |
| Received:September 14, 2017 Revised:October 09, 2017 |
| DOI：10.13241/j.cnki.pmb.2018.01.036 |
| 中文关键词: 前哨淋巴结 检测方法 肿瘤 |
| 英文关键词: Sentinel lymph node Test method Tumour |
| 基金项目:国家自然科学基金项目（81372795） |
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| 中文摘要: |
| 摘要：前哨淋巴结（sentinel lymph node，SLN）是肿瘤淋巴结转移的第一站，SLN活检肿瘤阳性的患者需要做系统性淋巴结清扫；SLN活检阴性的患者，不需要做系统性淋巴结清扫，可以缩短手术时间，降低手术费用，减少手术并发症；目前识别SLN的方法包括生物活性染料示踪法，放射性核素示踪法，联合示踪法，纳米炭（carbon nanoparticles，CNP）标记前哨淋巴结活检技术以及吲哚菁绿（Indocyanine Green，ICG）荧光标记法。SLN活检技术在乳腺癌、甲状腺癌、胃癌、恶性黑色素瘤、宫颈癌、子宫内膜癌等肿瘤中皆有不同程度的研究。本文通过复习文献，对前哨淋巴结检测方法予以归纳及其在常见肿瘤中的研究进展予以综述，旨在为恶性肿瘤临床治疗提供参考。 |
| 英文摘要: |
| ABSTRACT: Sentinel lymph node is the first station of lymph node metastasis, Patients with positive sentinel lymph node biopsy re- quire systematic lymph node dissection, whereas the negative patients do not which can shorten the operation time, reduce the cost of op- eration and complications. Currently, recognition method of sentinel lymph nodes including the biological activity of dye tracer method, radionuclide tracer method, combined tracer method ，carbon nanoparticles labeled sentinel lymph node biopsy and indocyanine green fluorescence labeling method. Sentinel lymph node biopsy has been studied in various degrees, including breast cancer, thyroid cancer, gastric cancer, malignant melanoma, cervical cancer and endometrial carcinoma. This article reviewed the literature and summarized the methods of sentinel lymph node detection and its progress in common tumors, aiming to provide reference for the clinical treatment of malignant tumors. |
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