Article Summary
张坤尧,曹瑞治,陈晓东,李 阳,叶燕彬.125I粒子联合深部热疗在骨转移瘤治疗中的应用[J].现代生物医学进展英文版,2017,17(35):6929-6933.
125I粒子联合深部热疗在骨转移瘤治疗中的应用
The Application of 125I Particles combined with Deep Hyperthermia in the Treatment of Bone Metastases
Received:August 02, 2017  Revised:August 25, 2017
DOI:10.13241/j.cnki.pmb.2017.35.030
中文关键词: 骨转移瘤  125I粒子  深部热疗
英文关键词: Bone metastasis  125I particles  Deep hyperthermia
基金项目:
Author NameAffiliationE-mail
张坤尧 遵义医学院 广东 珠海 519000 fengliangzh16@163.com 
曹瑞治 遵义医学院附属深圳市龙岗中心医院骨关节科 广东 深圳 528200  
陈晓东 遵义医学院 广东 珠海 519000  
李 阳 遵义医学院 广东 珠海 519000  
叶燕彬 遵义医学院 广东 珠海 519000  
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中文摘要:
      摘要 目的:探讨125I粒子植入联合深部热疗治疗骨转移瘤的临床疗效。方法:将63例骨转移瘤患者随机分为125I粒子植入联合深部热疗治疗组和单独采用125I粒子植入的对照组,比较分析两组患者治疗后的疼痛缓解情况与临床疗效差异。结果:两组患者治疗期间未出现严重不良反应;两组患者治疗后疼痛缓解,但治疗组缓解更明显,具有统计学意义;治疗组患者的局部病灶完全缓解率明显高于对照组。结论:125I粒子植入联合深部热疗在骨转移瘤的治疗中疗效确切,不良反应小,是一种值得推广的治疗方法。
英文摘要:
      ABSTRACT Objective: To investigate the 125I implantation combined with hyperthermia treatment of metastatic bone tumor pa- tients. Methods: 63 cases with bone metastases were randomly divided into control group 125I implantation combined with hyperthermia treatment group and separately using 125I implantation, comparative analysis of two groups of patients after treatment of pain relief and the difference of clinical efficacy. Results: Two groups of patients during treatment did not appear serious adverse reactions; pain relief after treatment in two groups, but the treatment group was significantly milder, with statistical significance; local lesions of patients in the treatment group complete remission rate was significantly higher than the control group. Conclusion: 125I implantation combined with hy- perthermia in boneThe curative effect for the treatment of metastatic tumor in the exact, less adverse reactions, it is worthy of promotion of treatment.
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