| 谭小嫣,马建刚,肖国强,詹小英,顾伟伟.经颅多普勒超声对脑梗死患者颅内动脉狭窄中的诊断价值研究[J].现代生物医学进展英文版,2017,17(25):4924-4927. |
| 经颅多普勒超声对脑梗死患者颅内动脉狭窄中的诊断价值研究 |
| Study the Diagnosis Value of Transcranial Doppler Ultrasound for Intracranial Artery Stenosis in Patients with Cerebral Infarction |
| Received:February 15, 2017 Revised:March 13, 2017 |
| DOI：10.13241/j.cnki.pmb.2017.25.030 |
| 中文关键词: 经颅多普勒超声 脑梗死 颅内动脉狭窄 诊断价值 |
| 英文关键词: Transcranial doppler ultrasound Cerebral infarction Intracranial arterial stenosis Diagnostic value |
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| 中文摘要: |
| 摘要 目的：研究经颅多普勒超声（TCD）对脑梗死患者颅内动脉狭窄中的诊断价值。方法：选择2014年10月至2016年10月新疆心脑血管病医院神经内科收治的急性脑梗死患者、短暂性脑缺血发作患者及后循环缺血发作患者共140例作为研究对象，对所有患者进行CT血管造影（CTA）及TCD检测。以CTA检查结果为金标准，对比两组颅内动脉狭窄的检测结果，分析TCD的诊断价值以及TCD对双侧大脑的中动脉（MCA）狭窄程度的诊断结果。结果：CTA诊断结果显示140例患者总共检出105例有颅内动脉狭窄，在1155条颅内段的前、后循环血管内，经CTA检测显示狭窄血管249条，TCD检测显示狭窄血管236条。与CTA相比，TCD对患者的诊断一致性较好（Kappa值＞0.75）。其中TCD对MCA的诊断敏感度和阳性预测值最高，分别为91.26%和93.07%，一致性最好（Kappa值=0.917）。210条MCA血管经CTA诊断结果显示狭窄103条，其中轻度狭窄17条，中度狭窄41条，重度狭窄45条，TCD诊断结果显示狭窄101条，其中轻度狭窄16条，中度狭窄40条，重度狭窄45条。经Kappa检验发现，TCD对MCA狭窄程度的诊断结果与CTA的一致性较好（Kappa值=0.884）。结论：TCD对于脑梗死患者的颅内动脉狭窄具有较高的诊断价值，且与CTA的诊断一致性较好。 |
| 英文摘要: |
| ABSTRACT Objective: To study the diagnosis value of Transcranial Doppler ultrasound for intracranial artery stenosis in patients with cerebral infarction. Methods: A total of 140 patients with acute cerebral infarction, transient ischemic attack and posterior circulation ischemic attack in Department of Neurology, Xinjiang cardiovascular and cerebrovascular disease hospital from October 2014 to October 2016 were selected as research object, CT angiography (CTA) and TCD detection were performed in all patients. Used CTA examination results as the gold standard, the detection results of intracranial artery stenosis in two groups were compared, the diagnostic value of TCD and the diagnostic results of TCD to the degree of bilateral middle cerebral artery (MCA) stenosis were analyzed. Results: CTA diagnosis showed that 140 patients had a total of 105 patients with intracranial artery stenosis, in the anterior and posterior circulation vessel of 1155 intracranial segments, CTA detection showed that 249 vessels were narrow, TCD detection showed that 236 vessels were narrow. Com- pared with CTA, TCD was better in the diagnosis of patients (Kappa value＞0.75). The diagnostic sensitivity and positive predic- tive value of TCD for MCA were the highest, which were 91.26% and 93.07%, the consistency was the best (Kappa value =0.917). CTA detection showed that 210 MCA vessels had 103 stenoses, mild stenosis 17, moderate stenosis 41, severe stenosis 45, TCD detection showed that the stenosis was 101, mild stenosis 16,moderate stenosis 40, severe stenosis 45. The Kappa test showed that the diagnostic results of TCD to the degree of MCA stenosis was better consistency compared with CTA (Kappa value=0.884. Conclusion: TCD has a high diagnostic value for cerebral artery stenosis in patients with cerebral infarction,and it is consistent with the diagnosis of CTA. |
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