| 陈 娟,陈超伍,陈炜炜,刘 军,朱海杭,邓登豪.国产奥西康与进口洛赛克治疗消化性溃疡出血的临床观察[J].现代生物医学进展英文版,2017,17(25):4896-4899. |
| 国产奥西康与进口洛赛克治疗消化性溃疡出血的临床观察 |
| Clinical Observation of Domestic Aoxikang and Imported Losec in the Treatment of Peptic Ulcer Bleeding |
| Received:March 06, 2017 Revised:April 02, 2017 |
| DOI：10.13241/j.cnki.pmb.2017.25.023 |
| 中文关键词: 消化性溃疡 奥西康 洛赛克 疗效 |
| 英文关键词: Peptic ulcer Aoxikang Losec Curative effect |
| 基金项目: |
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| 中文摘要: |
| 摘要 目的：对比国产与进口奥美拉唑注射治疗消化性溃疡出血的临床效果。方法：按照电脑产生的随机数列将2013年4月至2015年5月期间在我院消化科接受治疗的118例患者随机分为2组各59例，对照组给予进口药物洛赛克进行治疗，研究组给予国产药物奥西康进行治疗，两组均连续治疗7天，比较胃肠道反应、头晕及心悸发生率，平均治疗时间，以及临床治疗效果，另外分析两组患者的治疗成本。结果：研究组患者胃肠道反应、头晕及心悸发生率以及平均治疗时间与对照组比较差异无统计学意义（P>0.05）；两组治疗效果经过秩和检验整体差异无统计学意义（P＞0.05），且治疗总有效率相当（96.61% vs 94.91%），差异无统计学意义（P＞0.05）；使用国产药的成本低于进口药物。结论：国产奥西康与进口洛赛克治疗消化性溃疡出血临床疗效无明显差异，均能有良好的治疗效果，但其经济性更好。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the clinical effect of domestic and imported omeprazole injection in the treatment of peptic ul- cer bleeding. Methods: According to the random sequence generated by the computer, 118 patients who were treated in digestive depart- ment of our hospital from April 2013 to May 2015 were randomly divided into 2 groups, 59 cases in each group.The control group was given treatment of imported drug losec, while the study group was given treatment of domestic drug aoxikang, and two groups were treat- ed continuously for 7 days. The incidences of gastrointestinal reactions, dizziness and palpitations, the average treatment time, and clinical therapeutic effects were compared, in addition, the costs of treatment in the two groups were analyzed. Results: There were no significant differences in the incidences of gastrointestinal reactions, dizziness and palpitations and the average treatment time between the study group and the control group (P>0.05). There was no significant difference between the two groups in the treatment effect after rank sum test (P>0.05). The total effective rates (96.61% vs 94.91%) were equivalent, the differences were not statistically significant (P>0.05), but the costs of using domestic drugs were lower than that of imported drugs. Conclusion: The clinical curative effects of domestic aoxikang and imported losec in treatment of peptic ulcer bleeding have no significant difference, which can have a good therapeutic effect, but the economy of aoxikang is more better. |
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