| 朱嘉丽,李养军,赵云鹤,付金京,惠 靓,白晓宁.单切口与双切口有晶体眼后房型人工晶体植入术治疗高度近视的疗效对比[J].现代生物医学进展英文版,2017,17(23):4586-4589. |
| 单切口与双切口有晶体眼后房型人工晶体植入术治疗高度近视的疗效对比 |
| Comparison of the Efficacy of Single-incision and Two-incision Posterior Chamber Phakic Intraocularlens Implantation in the Correction of Extreme Myopia |
| Received:January 04, 2017 Revised:January 29, 2017 |
| DOI：10.13241/j.cnki.pmb.2017.23.045 |
| 中文关键词: 有晶体眼后房型ICL植入术 切口 临床疗效 并发症 |
| 英文关键词: Posterior chamber phakic intraocularlens implantation Incision Clinical effect Complication |
| 基金项目: |
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| 中文摘要: |
| 摘要 目的：观察和比较单切口与双切口有晶体眼后房型人工晶体植入术治疗高度近视的疗效和安全性。方法：将2011年1月至2013年6月间40例行常规双切口ICL植入术(80眼)患者设为对照组，2013年7月~2016年1月间40例行单切口ICL植入术(80眼)患者设为观察组。比较两组手术前后的裸眼视力、最佳矫正视力、手术安全性指数、有效性指数、屈光度(柱镜、等效球镜度数)、眼压、ECD、前房深度及并发症的发生情况。结果：术后6个月时，两组的裸眼视力均较术前显著提高(P<0.05)，且观察组的显著高于对照组(P<0.05)；观察组的手术安全性指数和有效性指数均显著高于对照组(P<0.05)。术后6个月时，两组的柱镜、等效球镜度数均较术前显著改善，且观察组的显著优于对照组(P>0.05)；术后两组的眼压、前房深度比较差异均无统计学意义(P<0.05)；对照组术后角膜内皮细胞计数(ECL)较术前显著降低(P>0.05)，观察组术后ECD与术前比较差异均无统计学意义(P<0.05)，ECD显著高于对照组(P<0.05)。术后6个月内，观察组的并发症发生率显著低于对照组(P<0.05)。结论：与双切口术比较，单切口有晶体眼后房型ICL植入术治疗高度近视临床效果显著，安全性更高。 |
| 英文摘要: |
| ABSTRACT Objective: To observe and compare the clinical effect of single-incision and two-incision posterior chamber phakic intraocularlens implantation in the correction of extreme myopia. Methods: 40 cases(80 eyes) of patients with extreme myopia underwent conventional two-incision posterior chamber phakic intraocularlens implantation in our hospital from January 2011 to June 2013 were selected as the control group and 40 cases(80 eyes) underwent single-incision posterior chamber phakic intraocularlens implantation from July 2013 to January 2016 were selected as observation group. The open hole before and after operation, best corrected visual acuity of vision, operation safety, effectiveness index, diopter (column mirror, equivalent ball for eyeglasses), intraocular pressure, ECD, anterior chamber depth and occurrence of complications were compared between two groups. Results: The uncorrected visual acuity(UCVA) of both groups at 6 months after operation were significantly higher than those before operation(P<0.05), which was significantly higher in the observation group than that of the control group(P<0.05); The operation safety and effectiveness index of observation group were significantly higher than those of the control group(P<0.05); The cylinder and spherical equivalent degree of both groups at 6 months after operation were significantly better than those before operation(P<0.05), which was significantly better in the observation group than that of the control group(P<0.05). The corneal endothelial cell counts(ECL) of control group after operation was significantly lower than that before operation(P<0.05), and no significant difference was found in the ECL of observation group before and after operation(P>0.05). The ECL of observation group after operation was significantly higher than that of the control group (P<0.05); The incidence rate of complication in observation group was significantly lower than that of the control group (P<0.05). Conclusion: Compared with two-incision operation, the single-incision posterior chamber phakic intraocularlens implantation had remarkable clinical effect in the correction of extreme myopia with higher security. |
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