| 韩 淼,周长明,高 英,思 超,刘 妮.超声引导下微波消融术治疗良性甲状腺结节的疗效及安全性分析[J].现代生物医学进展英文版,2017,17(21):4089-4092. |
| 超声引导下微波消融术治疗良性甲状腺结节的疗效及安全性分析 |
| Analysis of the Efficacy and Safety of Ultrasound-guided Percutaneous Microwave Ablation in the Treatment of Benign Thyroid Nodules |
| Received:October 23, 2016 Revised:November 20, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.21.022 |
| 中文关键词: 微波消融术 良性甲状腺结节 安全性 |
| 英文关键词: Microwave ablation Benign thyroid nodules Security |
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| 中文摘要: |
| 摘要 目的：分析超声引导下微波消融术治疗良性甲状腺结节的疗效及安全性。方法：选择2013年1月-2015年1月入住我院治疗的100例良性甲状腺结节患者，分成微波消融术组、常规手术组进行治疗。对2组患者术前后的血清指标(IL-6、CRP、TNF-α)进行检测和比较，并比较两组患者的手术时间、术中出血量、术后住院时间及并发症的发生情况。结果：两组患者术后的血清CRP、IL-6、TNF-α水平均较术前升高，但超声引导微波消融手术前后的CRP及IL-6变化程度不大(P>0.05)，术后TNF-α水平低于传统手术组(P<0.05)。微波消融手术出血量(12.34±0.99 mL)比传统手术出血量(28.75±2.15 mL)少，手术时间(28.46±2.63 min)比传统手术(84.05±6.95 min)短，术后住院时间(1.45±0.43 d)比常规手术(3.5±0.41 d)短，差异均具有统计学意义(P<0.05)。两组患者术后并发症发生率比较差异无统计学意义(P>0.05)。结论：超声引导下微波消融治疗甲状腺良性结节的疗效肯定，安全性高，对机体创伤较小，无手术瘢痕。 |
| 英文摘要: |
| ABSTRACT Objective: To analyze the efficacy and safety of ultrasound-guided percutaneous microwave ablation in the treatment of benign thyroid nodules. Methods: 100 patients admitted in our hospital from Jan 2013 to Jan 2015 were selected and divided into the microwave ablation group and conventional surgery group. After surgical treatment, the serum IL-6, CRP, TNF-α levels before and after treatment, duration of surgery, intra-operative blood loss, hospital stay and incidence of complications were compared between two groups. Results: After surgery, the serum levels of CRP, IL-6 and TNF-α were all higher than those before surgery in both groups, but the changes of CRP and IL-6 in microwave ablation group showed no significant difference, the level of TNF-α after surgery was lower than that of the traditional surgery group. The intra-operative blood loss(12.34±0.99 mL) of microwave ablation group were significantly lower than that of the conventional surgery group (28.75±2.15 mL)(P< 0.05); the operation time of microwave ablation surgery(28.46± 2.63 min) was obviously shorter than that of the conventional surgery group(84.05±6.95 min)(P<0.05), the hospital time of microwave ablation group(1.45±0.43 d) was also obviously shorter than that of the conventional surgery group(3.5±0.41 d)(P<0.05). No signifi- cant difference was found in the postoperative complication rate between two groups(P>0.05). Conclusion: Ultrasound-guided percuta- neous microwave ablation was safe and effective in the treatment of benign thyroid nodules without surgical scar on the body. |
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