| 杨少峰,赵和平,龚继涛,郑海明,刘鲜妮.功能性鼻内窥镜手术治疗鼻窦炎与鼻息肉的疗效分析[J].现代生物医学进展英文版,2017,17(18):3506-3508. |
| 功能性鼻内窥镜手术治疗鼻窦炎与鼻息肉的疗效分析 |
| Effective Analysis of Functional Endoscopic Sinus Surgery in Treatment of Sinusitis and Nasal Polyps |
| Received:September 27, 2016 Revised:October 21, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.18.024 |
| 中文关键词: 功能性鼻内窥镜手术 鼻窦炎 鼻息肉 炎症反应 生活质量 |
| 英文关键词: Functional endoscopic sinus surgery Sinusitis Nasal polyps Inflammatory response Quality of life |
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| 中文摘要: |
| 摘要 目的：探讨功能性鼻内窥镜手术治疗鼻窦炎与鼻息肉的疗效。方法：选取350例鼻窦炎与鼻息肉患者，按随机数字表法分为两组，对照组(164例) 给予综合疗法，观察组(186例) 给予功能性鼻内窥镜手术联合综合疗法。通过观察并记录疗效，治疗前，治疗后3个月患者体内IL-1，IL-8水平，SF-36量表评分，评价功能性鼻内窥镜手术治疗鼻窦炎与鼻息肉的疗效。结果：经手术和药物治疗，观察组有效率明显高于对照组(P<0.05)，治疗前，两组IL-1和IL-8水平无统计学差异(P>0.05)，治疗后3个月，两组IL-1和IL-8水平均明显下降，且观察组IL-1和IL-8水平低于对照组(P<0.05)，治疗前，两组SF-36各项评分无统计学差异，治疗后3个月，两组SF-36评分均明显增加(P<0.05)。观察组在躯体疼痛和总体健康2项评分明显高于对照组(P<0.05)，其余6项评分相比无统计学差异(P>0.05)。结论：功能性鼻内窥镜手术对鼻窦炎与鼻息肉具有较好的疗效，能显著减轻炎症反应，改善患者生活质量，值得临床推广使用。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the curative effect of functional endoscopic sinus surgery in treatment of sinusitis and nasal polyps. Methods: 350 cases of patients with sinusitis and nasal polyps were selected and randomly divided into two groups. The control group (164 cases) was given comprehensive treatment. The observation group (186 cases) was given functional endoscopic sinus surgery combined with comprehensive treatment. The effect of functional endoscopic sinus surgery in treatment of sinusitis and nasal polyps was evaluated by efficacy, IL-1, IL-8 level and SF-36 scores before treatment, 3 months after treatment. Results: After surgery and medicine treatment, the effective rate of observation group was higher in observation group than that of the control group(P<0.05). Before treatment, there were no statistical significance in IL-1, IL-8 level between two groups(P>0.05). 3 months after treatment, the IL-1 and IL-8 level were decreased in two groups. The IL-1 and IL-8 level of observation group was lower than that of the control group (P<0.05). Before treatment, there was no statistical significance in SF-36 scores. 3 months after treatment, the SF-36 scores were increased in two groups (P<0.05). The physical pain and health scores of observation group were higher than those of the control group (P<0.05). And the other 6 scores were not statistically significant (P>0.05). Conclusion: The functional endoscopic sinus surgery has a good effect on sinusitis and nasal polyps, it could reduce the inflammatory reaction, improve the quality of life, s worthy of clinical application. |
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