| 宋 伟,杨 科,高智勇,周 强,袁武雄.经尿道电切术与经尿道双极等离子电切术治疗非肌层浸润性膀胱肿瘤的疗效比较研究[J].现代生物医学进展英文版,2017,17(18):3490-3493. |
| 经尿道电切术与经尿道双极等离子电切术治疗非肌层浸润性膀胱肿瘤的疗效比较研究 |
| Non Muscle Invasive Bladder Cancer: Comparison of Transurethral Resection of Bladder Tumor and Transurethral Bipolar Plasmakinetic Resection |
| Received:March 02, 2017 Revised:March 26, 2017 |
| DOI：10.13241/j.cnki.pmb.2017.18.020 |
| 中文关键词: 经尿道电切术 经尿道双极等离子电切术 非肌层浸润性膀胱肿瘤 临床疗效 |
| 英文关键词: Transurethral resection of bladder tumor Transurethral bipolar plasmakinetic resection Non muscle invasive bladder cancer Clinical efficacy |
| 基金项目: |
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| 中文摘要: |
| 摘要 目的：探讨并对比经尿道电切术（TURBT）与经尿道双极等离子电切术治疗非肌层浸润性膀胱肿瘤（NMIBC）的疗效。方法：选取2012年1月到2016年1月在我院接受治疗的NMIBC患者76例 ，按照随机数字表法将患者分为观察组和对照组各38例，观察组采用经尿道双极等离子电切术进行治疗，对照组采用TURBT进行治疗。对比两组患者手术时间、术中出血量、术后导尿管留置时间、住院时间和手术并发症发生率，对比两组患者1年内复发率。结果：观察组的手术时间、术中出血量、术后导尿管留置时间、住院时间均显著少于对照组，差异有统计学意义（P<0.05）。两组患者膀胱穿孔和尿道内口狭窄发生率比较差异无统计学意义（P>0.05）。观察组闭孔神经反射发生率为7.89%（3/38），显著低于对照组的28.95%（11/38）,差异有统计学意义（P<0.05）。观察组患者1年内复发率为7.89%（3/38），对照组患者1年内复发率为10.53%（4/38），两者比较差异无统计学意义（P>0.05）。结论：经尿道双极等离子电切术治疗NMIBC能有效减少手术时间、术中出血量、术后导尿管留置时间、住院时间和闭孔神经反射发生率，安全有效，与TURBT相比优势明显，值得临床推广应用。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the curative effect of transurethral resection of bladder tumor (TURBT) and transurethral bipolar plasmakinetic resection in the treatment of non muscle invasive bladder cancer (NMIBC). Methods: A total of 76 patients with NMIBC, who were treated in Hunan Provincial People's Hospital from January 2012 to January 2016, were selected and randomly divided into observation group(n=38) and control group(n=38). The observation group was treated with transurethral bipolar plasmakinetic resection;the control group, with TURBT. The operation time, intraoperative blood loss, postoperative indwelling time of catheter, hospitalization time,complications and the recurrence rate within 1 year were compared between the two groups. Results: The operation time, intraoperative blood loss, postoperative indwelling time of catheter, hospitalization time in the observation group were significantly lower than those in the control group, the differences were statistically significant(P<0.05). There were no significant differences in the incidence of bladder perforation and stricture of urethral stricture between the two groups (P>0.05). The incidence of obturator nerve reflex of observation group was 7.89%(3/38), the incidence of obturator nerve reflex of control group was 28.95%(11/38), the difference was statistically significant(P<0.05). The recurrence rate[7.89%(3/38)] within 1 year of the observation group was lower than that[10.53% (4/38)] of the control group, there was no significant difference between the two groups(P>0.05). Conclusion: Compare with TURBT, transurethral bipolar plasmakinetic resection in the treatment of NMIBC can effectively reduce the operation time, intraoperative blood loss, postoperative indwelling time of catheter, hospitalization time and the incidence of obturator nerve reflex, safe and effective, which is worthy of clinical application. |
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