| 东 敏,刘建华,张 励,阮正一,陈 燕.宫颈癌患者行根治性子宫切除术且保留盆腔自主神经的效果观察[J].现代生物医学进展英文版,2017,17(16):3054-3056. |
| 宫颈癌患者行根治性子宫切除术且保留盆腔自主神经的效果观察 |
| The Clinical Effect of Radical Hysterectomy with Reservation of Pelvic Autonomic Nerve for Cervical Cancer Patients |
| Received:October 25, 2016 Revised:November 20, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.16.013 |
| 中文关键词: 盆腔自主神经 宫颈癌 根治性手术 子宫切除术 临床效果 |
| 英文关键词: Pelvic autonomic nerve Cervical carcinoma Radical operation Hysterectomy Clinical effect |
| 基金项目:上海市科委基金项目(20113140 ) |
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| 中文摘要: |
| 摘要 目的：探讨宫颈癌患者行保留盆腔自主神经的根治性子宫切除术的临床效果。方法：按照随机数字表法将入选的48例宫颈癌患者随机分为对照组和试验组两组，每组患者各24例，其中对照组患者均采用传统的宫颈癌根治手术治疗，而试验组患者则采用保留盆腔自主神经的根治性子宫切除术进行治疗，比较两组患者的术中情况和术后恢复情况等。结果：两组患者的子宫切除出血量和术中总出血量以及术中输血率均无明显差异（均P＞0.05），但是试验组患者的子宫切除时间和手术总时间显著长于对照组患者（t=2.934，P＜0.05；t=3.121，P＜0.05）。两组患者之间的术后排气、排便时间均无明显差异（均P＞0.05），提示两组患者术后直肠功能无明显差异；对照组患者的术后残余尿量＜100ml时间与术后残余尿量＜50ml时间均显著高于试验组患者（t=2.891，P＜0.05；t=3.092，P＜0.05）。术后试验组患者的首次排尿感和急迫排尿感以及最大腹压等均显著低于对照组患者（t=4.283，P＜0.05；t=4.027，P＜0.05；t=3.137，P＜0.05）；而最大膀胱压和最大尿流量以及最大逼尿肌压等则显著高于对照组（t=3.192，P＜0.05；t=2.938，P＜0.05；t=3.572，P＜0.05）。结论：采取保留盆腔自主神经的根治性子宫切除术能够较好地减少宫颈癌患者临床并发症的出现，具有较好的治疗效果，值得加以推广和运用。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinical effect of radical hysterectomy with pelvic autonomic nerve reservation for cervical cancer patients. Methods: 48 cases of patients with cervical cancer were selected in our hospital from January 2011 to January 2016. According to the random number table method, all patients were divided into control group and experimental group, each group with 24 cases. Patients in the control group were treated with traditional cervical cancer radical surgery, while those in experimental group had radical hysterectomy with reservation of pelvic autonomic nerve. Compare intraoperative states and postoperative recovery between two groups. Results: There were no significant differences in uterus resection bleeding volume, intraoperative total bleeding volume and intraoperative blood transfusion rate between two groups (P > 0.05). However, the experimental group had longer uterus resection time and total operation time than the control group (t =2.934, P < 0.05; t =3.121, P < 0.05). Between the two groups, there was no significant difference in postoperative exhaust and defecate time (P > 0.05), indicating that patients in the two groups had no significant difference in rectal function after operation; The time for patients with postoperative residual urine volume < 100ml and time for postoperative residual urine volume < 50 mL were significantly longer in control group than in experimental group (t=2.891, P < 0.05; t=3.092, P < 0.05). After operation, the urine volume at the first urination sensation and urgent urination sensation and the abdominal pressure were significantly less in experimental group than in control group (t=4.283, P < 0.05; t=4.027, P < 0.05; t=3.137, P < 0.05). Whereas, maximum bladder pressure, maximum urinary flow rate and maximum detrusor pressure all were significantly higher in experimental group than in control group (t=3.192, P<0.05; t=2.938, P<0.05; t=3.572, P<0.05). Conclusion: The radical hysterectomy with reservation of pelvic autonomic nerve can reduce the clinical complications of patients with cervical cancer. It had good therapeutic effect, and is worth popularizing and applying. |
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