| 孔宪诚,黄建平,沙 粒,汤雪峰,阎 良.经腹腔镜实施结直肠癌根治术对高龄患者胃肠功能的影响[J].现代生物医学进展英文版,2017,17(9):1700-1702. |
| 经腹腔镜实施结直肠癌根治术对高龄患者胃肠功能的影响 |
| Effects of Laparoscopic Radical Resection of Colorectal Cancer on Gastrointestinal Function in Elderly Patients with Colorectal Cancer |
| Received:August 10, 2016 Revised:August 30, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.09.026 |
| 中文关键词: 结直肠癌根治术 胃肠功能 腹腔镜 高龄患者 |
| 英文关键词: Radical resection of colorectal cancer Gastrointestinal function Laparoscope Elderly patients |
| 基金项目:国家卫生计生委医药卫生科技发展研究中心支撑项目(W2015RQ36) |
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| 中文摘要: |
| 摘要 目的：探讨结直肠癌高龄患者经腹腔镜实施结直肠癌根治术对胃肠功能产生的影响。方法：选取92例接受结直肠癌根治手术的结直肠癌患者，将其随机数字表法随机分为试验组和对照组两组，其中对照组患者均采用开腹手术进行治疗，而试验组患者则采取腹腔镜下结直肠癌根治手术。观察比较两组患者的术中情况和术后的胃肠功能。结果：两组患者之间的淋巴结清扫数目和标本切除长度均无明显差异（均P＞0.05），试验组患者的术中出血量以及手术时间均低于对照组患者（t=10.394，P＜0.05；t=6.983，P＜0.05）。胃泌素和胃动素水平和患者术后的肛门排气时间以及腹胀持续时间呈显著的负相关关系；试验组患者的术后肛门排气时间和腹胀持续时间均低于对照组患者，并且其胃泌素和胃动素含量均明显高于对照组患者（均P＜0.05）。结论：腹腔镜下结直肠癌根治手术较开腹手术具有创伤小的优势，并且对于高龄结直肠癌患者术后的胃肠功能具有较好的恢复效果。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of laparoscopic radical resection of colorectal cancer on gastrointestinal function in elderly patients with colorectal cancer. Methods: 92 cases of patients with colorectal cancer received radical resection of rectal cancer surgery. All enrolled patients were divided into two groups according to the random number table method, the test group and the control group. The patients in control group were treated by open surgery, while those in experimental group had laparoscopic colorectal cancer radical surgery. Compare the intraoperative and postoperative gastrointestinal function between two groups. Results: Between the two groups, no significant differences were observed in the number of lymph node dissection and the length of resection specimens (P>0.05). The intraoperative bleeding and operation time were significantly lower in experimental group than in control group (t=10.394, P<0.05; t=6.983, P<0.05). Gastrin and motilin levels showed a significant negative correlation with the postoperative anal exhaustion time and ab- dominal distention duration. The postoperative anal exhaust time and abdominal distention duration were significantly shorter in experi- mental group than in control group, and the levels of gastrin and motilin were significantly higher in experimental group than in control group (all P<0.05). Conclusion: Laparoscopic radical surgery for colorectal cancer had advantage of minimal invasion as compared with open surgery. And it has a good recovery effect on gastrointestinal function after operation in elderly patients with colorectal cancer. |
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