Article Summary
顾熙东 章晓鹰△ 徐金龙 陈君灏 杨森.病毒性心肌炎患者血清CK-MB、hs-CRP、IL-35 及cTnI水平的表达[J].现代生物医学进展英文版,2017,17(6):1099-1101.
病毒性心肌炎患者血清CK-MB、hs-CRP、IL-35 及cTnI水平的表达
Expression of SerumCK-MB, hs-CRP, IL-35 and cTnI Levels in ViralMyocarditis
  
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中文关键词: 病毒性心肌炎  CK-MB  hs-CRP  IL-35  cTnI
英文关键词: Viral myocarditis  CK-MB  hs-CRP  IL-35  cTnI
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Author NameAffiliation
顾熙东 章晓鹰△ 徐金龙 陈君灏 杨森 上海中医药大学附属曙光医院检验科 
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中文摘要:
      目的:研究血清肌酸激酶同工酶(CK-MB)、超敏C-反应蛋白(hs-CRP)、白介素-35(IL-35)和肌钙蛋白(cTnI)对病毒性心肌炎 的诊断意义。方法:研究对象为我院2012 年1 月至2015 年1 月间接受诊治的病毒性心肌炎病人63 例,作为实验组;选取我院同 时期健康体检人60 例为对照组。对照两组血清CK-MB、hs-CRP、IL-35及cTnI的检测水平。结果:实验组CK-MB、hs-CRP及cTnI 阳性率均明显高于对照组,差异有统计学意义(P<0.05);实验组的血清CK-MB、hs-CRP、IL-35 及cTnI 的检测结果均明显高于对 照组,差异有统计学意义(P<0.05);cTnI敏感度及特异度均是最高的,hs-CRP特异度高于CK-MB,但敏感度较低。结论:病毒性心 肌炎患者血清CK-MB、hs-CRP、IL-35及cTnI可作为诊断的重要指标。
英文摘要:
      Objective:To explore the diagnosis value of serum creatine kinase (CK-MB),high-sensitivity C-reactive protein (hs-CRP), interleukin-35 (IL-35) and troponin I (cTnI) in viral myocarditis.Methods:The research subjects were 63 cases of patients with viral myocarditis who diagnosed and accepted treatment in our hospital between January 2012 to January 2015, as the experimental group; while 60 cases of healthy people in our hospital as the same period as a control group. Compared the levels of serum CK-MB, hs-CRP, IL-35, and cTnI in two groups.Results:The positive rates of CK-MB, hs-CRP, cTnI in experimental group were significantly higher than control group, the differences were statistically significant(P<0.05); The levels of serum CK-MB, hs-CRP, L-35 and cTnI test results were significantly higher than the control group, the differences were statistically significant (P<0.05); The sensitivity and specificity of cTnI were highest, and the specificity of hs-CRP was higher than CK-MB, but the sensitivity was lower.Conclusion:Serum hs-CRP, CK-MB, cTnI and IL-35 can be used as an important indicator of the diagnosis of viral myocarditis.
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