| 荣为为,韩明子,金世柱,李瑞妮,崔承虎.骨髓间充质干细胞在组织工程研究中的应用新进展[J].现代生物医学进展英文版,2017,17(5):982-984. |
| 骨髓间充质干细胞在组织工程研究中的应用新进展 |
| New Application of Mesenchymal Stem Cells in the Field of Tissue-engineering Scientifical Research |
| Received:March 18, 2016 Revised:April 14, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.05.049 |
| 中文关键词: 骨髓间充质干细胞 诱导分化 组织工程 种子细胞 |
| 英文关键词: Bone marrow mesenchymal stem cells Inducing differentiation Tissue engineering Seed cells |
| 基金项目:国家自然科学基金面上项目（81370557） |
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| 中文摘要: |
| 摘要：骨髓间充质干细胞又称为骨髓源性间充质干细胞，是指存在于骨髓基质细胞系统中的一类干细胞，具有高度稳定的体外扩增能力和多向分化潜能等特点。骨髓间充质干细胞因其取材方便，易于分离和培养，以及在适当条件下可诱导分化为皮肤、骨骼、内脏、血液、神经等多种组织细胞的独特优势，目前被广泛应用于药物开发、免疫调节、组织修复、器官重建等多个研究领域。近年来，骨髓间充质干细胞作为种子细胞在组织工程领域有着非常诱人的潜在应用前景。本文就骨髓间充质干细胞在组织工程学研究中应用的最新进展作一综述。 |
| 英文摘要: |
| ABSTRACT: Bone marrow mesenchymal stem cells (BMSCs) also might be called bone marrow-derived mesenchymal stem cells, is a sort of stem cells existing in the bone marrow stromal cells system, and has general characteristics of stem cells, the highly stable am- plification ability in vitro and the potential of multi-directional differentiation. Given that BMSCs are convenient, easy to be isolated and cultured, and can be induced to differentiate into bones, blood, skin, gut, neural cells under appropriate conditions. BMSCs are widely used in many research fields, such as regenerative medicine, immune regulation, tissue repairing, organ reconstruction and so on, BMSCs as seed cells in tissue engineering field have a very promising potential application prospect. This paper reviewed the latest progress in tissue engineering applications of BMSCs. |
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