| 董莉 陶惠△ 王淑珍 许英 张美春.血清抑制素B评估成年隐睾患者术后睾丸功能恢复的临床价值[J].现代生物医学进展英文版,2017,17(2):363-365. |
| 血清抑制素B评估成年隐睾患者术后睾丸功能恢复的临床价值 |
| The Clinical Value of SerumInhibin B in the Evaluatation of TesticularFunction Recovery of Adult Patients after CryptorchidismSurgery* |
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| DOI： |
| 中文关键词: 血清抑制素B 隐睾 睾丸 功能 |
| 英文关键词: InhB Cryptorchidism Testicle Function recovery |
| 基金项目:国家自然科学基金项目(81170400) |
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| 中文摘要: |
| 目的：探讨血清抑制素B(InhB)用于评价成年隐睾患者术后睾丸功能恢复的临床价值。方法：收集2011 年10 月~2015 年9
月于我科就诊的138 例成年隐睾患者作为观察组，另收集100 例健康志愿者作为正常对照组。用双抗体夹心酶联免疫吸附法检
测观察组患者术前、术后30 天和90 天及正常对照组的血清InhB 水平，并参照WHO 人类精液检查与处理实验室手册(第五版)
方法进行精液常规检查。结果：与正常对照组比较，观察组患者术前、术后30天和90 天血清InhB 水平、精子活率、精子密度均明
显降低，差异均有统计学意义(P＜0.05)。观察组术后30 天血清InhB水平、精子活率、精子密度与术前比较差异均无统计学意义
(P＞0.05)，观察组术后90 天血清InhB水平、精子活率、精子密度明显高于术前，差异均有统计学意义(P＜0.05)。观察组组术前、术
后30 天和90 天的精液量与正常对照组对比差异均无统计学意义(P＞0.05)。观察组术前、术后30 天和90 天及正常对照组血清
InhB水平与精子浓度均呈正相关(观察组术前：r=0.81，P＜0.05，观察组术后30 天：r=0.78，P＜0.05，观察组术后90 天：r=0.84，P＜
0.05，正常对照组：r=0.77，P＜0.05)。结论：血清InhB 用于评估成年隐睾患者术后睾丸功能恢复具有一定的临床应用价值。 |
| 英文摘要: |
| Objective:To investigate the clinical value of serum InhB in the evaluation of testicular function recovery of adult
patients after cryptorchidism surgery.Methods:A retrospective study was performed on 138 patients with cryptorchidism(observation
group) and 100 healthy persons (control group). Double-antibody sandwich enzyme-linked immunosorbent assay was used to detect the
levels of InhB in serum of patients (preoperation and 30, 90 d postoperation) and healthy persons. Semen parameter according to WHO
laboratory manual for the examination and processing of human semen was deteted.Results:The levels of serum InhB, sperm motility
and sperm density preoperation and on the 30th, 90th day postoperation of observation group were obviously lower than those of the
control group (P<0.05). The levels of serum InhB, sperm motility and sperm density on the 30th day postoperation and preoperation of
observation group showed no significant difference(P>0.05). The levels of serum InhB, spermmotility and spermdensity on the 90th day
postoperation of observation group were obviously higher than those of observation group preoperation(P<0.05). The levels of ejaculation
sperm volume of observation group (preoperation and 30, 90 d postoperation) and control group showed no statistical significance(P>0.
05). The levels of serum InhB was positively correlated with the sperm density of observation group (preoperation and 30, 90 d
postoperation) and control group (observation group preoperation: r=0.81, P＜0.05, observation group 30 d postoperation: r=0.78, P＜
0.05, observation group 90 d postoperation: r=0.84, P＜0.05, control group: r=0.77, P＜0.05).Conclusion:InhB level could be helpful to
evaluate the recovery of testicular function after cryptorchidismsurgery of adult patients. |
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