| 刘建林 王岩松 王梓仪 翁瑶 张晓东.盐酸氨基葡萄糖片联合玻璃酸钠治疗颞下颌关节骨关节炎的疗效观察[J].现代生物医学进展英文版,2017,17(2):331-333. |
| 盐酸氨基葡萄糖片联合玻璃酸钠治疗颞下颌关节骨关节炎的疗效观察 |
| Efficacy of Glucosamine Hydrochloride Tablets combined with SodiumHyaluronate in the treatment of Temporomandibular Joint Osteoarthritis |
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| DOI： |
| 中文关键词: 盐酸氨基葡萄糖片 玻璃酸钠 颞下颌关节 骨关节炎 |
| 英文关键词: Glucosamine Hydrochloride Tablets Sodiumhyaluronate Temporomandibular joint Osteoarthritis |
| 基金项目:深圳市科技研发基金项目（JCYJ20120827172450676） |
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| 中文摘要: |
| 目的：研究盐酸氨基葡萄糖片联合玻璃酸钠治疗颞下颌关节骨关节炎（TMJOA）的临床疗效，为临床治疗提供依据。方法：选
取2012 年11 月到2015 年11 月我院收治的TMJOA 患者60 例，按照随机数字表法将患者分为研究组和对照组，每组30 例，两
组均给予玻璃酸钠关节腔注射，研究组在此基础上给予盐酸氨基葡萄糖片治疗，应用视觉模拟评分法（VAS）评价关节疼痛情况，
比较两组临床疗效和不良反应，比较治疗前后两组最大张口度、张口VAS 评分和张口偏斜。结果：研究组总有效率为83.33％
（25/30），显著高于对照组的56.67％（17/30），比较差异具有统计学意义（P＜0.05）；治疗后两组张口VAS 评分和张口偏斜显著降
低，最大张口度显著增高，且研究组显著优于对照组，比较差异具有统计学意义（P＜0.05）；两组不良反应发生率比较差异无统计
学意义（P＞0.05）。结论：盐酸氨基葡萄糖片联合玻璃酸钠治疗TMJOA 具有较好的临床疗效，能有效改善患者关节功能。 |
| 英文摘要: |
| Objective:To study the clinical efficacy of Glucosamine Hydrochloride Tablets combined with sodium hyaluronate in
the treatment of Temporomandibular joint osteoarthritis (TMJOA), to provide basis for clinical treatment.Methods:60 cases of TMJOA
who were treated in our hospital from November 2012 to November 2015 were selected, the patients were divided into study group and
control group according to the random number table method, 30 cases in each group. Two groups were given sodium hyaluronate
injection, the study group was given Glucosamine Hydrochloride Tablets treatment. Evaluated the joint pain with visual analogue scale
(VAS), the clinical efficacy and adverse reactions of the two groups were compared, the maximummouth opening, mouth VAS score and
mouth deviation of two groups were compared.Results:The total effective rate of the study group was 83.33%(25/30), which was
significantly higher than that of 56.67%(17/30) in the control group,the difference was statistically significant (P<0.05); The VAS score
and the mouth opening deviation after treatment of the two groups were significantly decreased, maximum mouth opening increased
significantly, and the study group was significantly better than the control group, the differences were statistically significant (P<0.05);
There was no statistically significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:Glucosamine Hydrochloride Tablets combined with sodiumhyaluronate in the treatment of TMJOA has good clinical efficacy, which can
effectively improve the patient's joint function. |
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