| 宁佩芳,陈立群,刘 君,孟 晓,李 墨,张 勇.卵巢囊性颗粒细胞瘤的临床病理学特征、诊断及鉴别诊断[J].现代生物医学进展英文版,2017,17(1):152-154. |
| 卵巢囊性颗粒细胞瘤的临床病理学特征、诊断及鉴别诊断 |
| Clinicopathologic Features, Diagnosis and Differential Diagnosis of Ovarian Cystic Granulosa Cell Tumor |
| Received:June 30, 2016 Revised:July 10, 2016 |
| DOI：10.13241/j.cnki.pmb.2017.01.039 |
| 中文关键词: 卵巢 囊性颗粒细胞瘤 病理诊断 |
| 英文关键词: Ovary Cystic granulosa cell tumor Pathological diagnosis |
| 基金项目:辽宁省科技攻关项目（2012225016） |
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| 中文摘要: |
| 摘要 目的：探讨卵巢囊性颗粒细胞瘤的临床病理学特征、诊断和鉴别诊断要点。方法：复习1例卵巢囊性颗粒细胞瘤患者的临床资料、肿物的大体以及镜下病理组织学特征、免疫组化染色特征。结果：患者左侧单房囊性颗粒细胞瘤，大小为14.6 cm×18.9 cm ×9.8 cm，囊壁厚薄不均一；镜下可见内壁由颗粒细胞组成，细胞层数不一，可见典型的Call-Exner小体；免疫组化染色可见α-in- hibin，Vimentin，CD99均阳性。结论：卵巢囊性颗粒细胞瘤可依据镜下发现不典型增生的颗粒细胞、典型的Call-Exner小体和核沟等特征性的组织形态学作出诊断。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the clinicopathologic features, diagnosis and differential diagnosis of ovarian cystic granulosa cell tumor. Methods: The clinical data of one case of ovarian cystic granulosa cell tumor were reviewed. And the gross and histological features of the tumor were studied. Results: The patient had a left-sided unilocular cystic granulosa cell tumor, with the size of 14.6 cm× 18.9 cm×9.8 cm and uneven thickness of capsule wall. Under the microscope, the wall was consisted of granule cell, and the cell layer was visible. The typical Call-Exner bodies were also found under the microscope. Immunohistochemical staining results indicated that the alpha - inhibin, vimentin and CD99 were positive. Conclusion: The cystic granule cell tumor of the ovary could be diagnosed on the base of the histological characteristics like microscopic finding of atypical proliferation of granulosa cells, typical Call-Exner bodies and nuclear grooves. |
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