毛智荣 屠春林 胡建荣 王珍 余艳芳 郑大炜.呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征分析[J].现代生物医学进展英文版,2015,15(35):6942-6944. |
呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征分析 |
Clinical Features of Ventilator-associated Pneumonia Infected with Acinetobacter Baumannii |
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DOI: |
中文关键词: 呼吸机相关肺炎 鲍氏不动杆菌 临床特征 |
英文关键词: entilator-associated pneumonia Acinetobacter baumannii Clinical features |
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中文摘要: |
目的:研究呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征。方法:选取2010 年1 月到2015 年1 月我院收治的应用呼吸
机患者130 例,根据是否合并肺炎鲍氏不动杆菌感染将患者分为研究组(86 例)和对照组(44 例),分析呼吸机相关性肺炎鲍氏不
动杆菌的临床特征,然后根据药敏实验选择应用药物进行治疗,并观察治疗效果。结果:呼吸机相关性肺炎鲍氏不动杆菌感染的
分布科室主要以ICU 为主,大约为76.74%,神经外科次之,大约为8.14%;研究组呼吸机应用时间(18.72± 3.15)天显著长于对照
组(6.18± 0.02)天,两组比较差异具有统计学意义(P<0.05);研究组经舒巴坦联合左氧氟沙星或者亚胺培南治疗后总有效率为
91.86%。结论:呼吸机相关性肺炎鲍氏不动杆菌多发生于ICU,且感染者呼吸机应用时间较长,联合治疗效果显著。 |
英文摘要: |
Objective:To study the clinical features of ventilator-associated pneumonia infected with Acinetobacter baumannii.Methods:A total of 130 patients, who were admitted to Central Hospital of Jiading District from January 2010 to January 2015 and underwent ventilator, were divided into study group(n=86) and control group(n=44) according to whether or not infected with Acinetobacter baumannii . The clinical features of ventilator-associated pneumonia infected with Acinetobacter baumannii were analyzed. The study group was treated with drugs picked from the drug sensitive test, and the therapeutic effect was observed.Results:Patients with ventilator- associated pneumonia infected with Acinetobacter baumannii were mainly distributed in ICU, accounting for 76.74%; neurosurgery followed, accounting for 8.14%. Ventilator application time (18.72± 3.15 days) in the study group was significantly longer than that (6.18± 0.02, days) in the control group, the difference was statistically significant (P<0.05). The total effective rate of study group after treated with sulbactam plus levofloxacin or imipenem was 91.86%.Conclusion:Ventilator-associated pneumonia infected with Acinetobacter baumannii often appears in ICU, and the ventilator application time of patients is longer.The combined treatment has a remarkable
effect. |
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