| Objective:To investigate the clinical effect and mechanism of amoxicillin combined with methylprednisolone on the
treatment of bronchial pneumonia for elderly patients.Methods:84 elderly patients with bronchial pneumonia who were treated in our
hospital were selected and randomly divided into the control group and the experimental group by different treatment. The clinical signs,
IgM, IgG, IgA, CD4+ and CD8+, NK cells and LDH3, LDH4 and HBDH levels were compared before and after treatment.Results:After
treatment, the recovery time of cough and asthma, hyperpyrexia, rhonchi and moist rales were significantly shorter than those of the control
group(P<0.05), the IgA, IgM, IgG, CD8+, NK cell levels and serum LDH, HBDH levels were lower(P<0.05), while the CD4+T lymphocyte
levels were significantly higher (P<0.05).Conclusion:Amoxicillin combined with methylprednisolone could significantly improve
the clinical symptoms of elderly patient with bronchial pneumonia, which might be related to the decrease of IgA, IgG, IgM, LDH,
HBDH levels and NK, CD8+T lymphocyte levels and enhancement of CD4+T lymphocyte levels. |
