| 王耀生 陈长青△ 沈保磊 周影 王成 林灿斌 陈峥龙.经皮椎间孔镜联合超前镇痛的术后疼痛的疗效分析[J].现代生物医学进展英文版,2016,16(32):6286-6289. |
| 经皮椎间孔镜联合超前镇痛的术后疼痛的疗效分析 |
| Effect of Percutaneous Intervertebral Foramen Microscopically andCollagenase Disc Injection Joint Advance Analgesia for Treatment ofPostoperative Pain after Disc Herniated Intervertebral Surgery |
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| DOI： |
| 中文关键词: 椎间孔镜 胶原酶 椎间盘突出症 疼痛 |
| 英文关键词: Intervertebral foramen microscopy Collagen enzyme Intervertebral disc herniation Pain |
| 基金项目:南京军区医学科技创新经费资助项目(11Z022) |
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| 中文摘要: |
| 目的：探讨经皮椎间孔镜联合盘内注射胶原酶对于椎间盘突出症术后疼痛的疗效。方法：选取我科收治的经皮椎间孔镜手术
患者110 例，将其随机分为观察组以及对照组，每组55 例，观察组采取椎间孔镜联合盘内注射胶原酶联合超前镇痛治疗，对照组
给予相同的手术方式联合术后口服药物治疗，连续治疗1 个疗程后，比较两组患者术后4、12、24、48、72 h的疼痛评分，观察两组
术后曲马多的用量，比较两组患者术后出现恶心、呕吐、嗜睡、便秘、皮肤瘙痒等并发症的发生情况，比较两组术前以及术后7、14
d 的JOA评分情况。结果：术后4、12、24、48、72 h 观察组的疼痛评分均明显低于对照组，观察两组术后曲马多的用量明显少于对
照组，观察组术后并发症的发生率为7.27 %（4/55），对照组为30.91 %（17/55），组间比较有明显差异（x2=13.624，P<0.05），术后7 d
观察组JOA评分明显优于对照组，P<0.05，术后14 d组间比较无明显差异，P>0.05。结论：塞来昔布超前镇痛措施应用于经皮椎间
孔镜联合盘内注射胶原酶治疗腰椎间盘突出症术后患者能够有效缓解术后疼痛，并减少术后阿片类药物的使用，改善术后功能，
值得临床推广应用。 |
| 英文摘要: |
| Objective:To study the effect of percutaneous intervertebral foramen microscopically and collagenase disc injection
joint advance the curative analgesia for treatment of postoperative pain after disc herniated intervertebral surgery.Methods:Selected 110
cases of patients who received percutaneous intervertebral foramen surgery in our department were randomly divided them into
observation group and control group,55 cases in each group. The patients in observation group were adopted percutaneous intervertebral
foramen microscopically and collagenase disc injection joint advance analgesia treatment, and the patients in control group were given
the same surgery joint postoperative oral drug therapy, and the patients in both group received a course of treatment. The pain score was
compared in postoperative 4, 12, 24, 48, 72 h in two groups, and the postoperative dosage of tramadol and pethidine was observed in two
groups, and the incidence of postoperative nausea, vomiting, lethargy, constipation, itchy skin and other complications was detected in
two groups, and the preoperative and postoperative JOA score of 7, 14 d was compared in two groups.Results:The postoperative 4, 12,
24, 48, 72 h pain score in observation group were significantly lower than that of the control group, and the postoperative dosage of
tramadol and pethidine of observation group was significantly less than that of the control group, and the incidence of postoperative
complications was 7.27%(4/55) in the observation group, while the control group was 30.91 %(17/55), and there was obvious statistical
difference between groups (x2 = 13.624, P < 0.05), and the postoperative 7 d JOA score of the observation group was obviously better
than the control group, P < 0.05, but JOA score in 14 d after surgery had no significant difference between groups (P>0.05).Conclusion:The percutaneous intervertebral foramen microscopically and collagenase disc injection joint advance analgesia can effectively relieve
postoperative pain and reduce postoperative opioid use, improve the postoperative function for treatment of postoperative pain after disc
herniated intervertebral surgery, worthy of clinical popularization and application. |
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