| 靳春鹏 刘树柏 潘天耀 黄磊 史越峰.以PD-1 为靶点的抗肿瘤药物专利现状分析[J].现代生物医学进展英文版,2016,16(31):6177-6181. |
| 以PD-1 为靶点的抗肿瘤药物专利现状分析 |
| Analysis on Patents of Anti-tumor Drugs Targeting PD-1 |
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| DOI： |
| 中文关键词: 肿瘤 药物 专利 德温特专利数据库 分析 |
| 英文关键词: Tumor Drug Patent DWPI Analysis |
| 基金项目: |
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| 中文摘要: |
| PD-1（程序性死亡受体1）是一种重要的免疫抑制分子，其与癌症的治疗密切相关。目前FDA（美国食品药品监督管理局）已
经批准了PD-1抑制剂抗体作为癌症治疗药，因此，PD-1 具有极高的研究和应用价值。目前在专利领域，全球各大药企均已经开
始专利布局，而在中国申请的专利也是日趋增多，对于我国企业来说，把握时机提前布局专利申请，有利于识别竞争对手，抢占市
场。本文通过分析以PD-1 为靶点的药物专利现状，特别是研究的重点领域，专利申请的国内重点布局等方面，为国内的申请人未
来的研发方向和专利布局提供适当的指引。 |
| 英文摘要: |
| Programmed cell death-1 (PD-1), an important immunosuppressive molecule, was involved in the treatment of cancers
and infectious diseases. Humanized antibody against human PD-1 has been approved by Food and Drug Administration (FDA) of
the United States as an investigational new drug, and PD-1 could be very valuable for the research and application. Currently, all of the
world's largest pharmaceutical companies have started patent layout in the field of PD-1. Because of the increasing application of the related
patent in China, advanced patent layout will benefit the local enterprise to identify competitors and capture the market prior. In this
paper, the statues of patents distribution in anti-tumor drugs targeting PD-1, especially applications in the key areas were analyzed, which
could direct internal applicants for appropriate research ideas and suitable patent application strategy. |
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