| 王韬甫 宋志冰 刘宿平 李新丹 娄勇.瑞芬太尼复合右美托咪定在心脏手术中的麻醉效果及对血流动力学的影响[J].现代生物医学进展英文版,2016,16(31):6107-6109. |
| 瑞芬太尼复合右美托咪定在心脏手术中的麻醉效果及对血流动力学的影响 |
| Anesthetic Effect of Remifentanil combined with Dexmedetomidine inCardiac Surgery and its Influence on Hemodynamics |
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| DOI： |
| 中文关键词: 瑞芬太尼 右美托咪定 心脏手术 麻醉 血流动力学 |
| 英文关键词: Remifentanil Dexmedetomidine Cardiac surgery Anesthetic Hemodynamics |
| 基金项目: |
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| 中文摘要: |
| 目的：分析瑞芬太尼（REM）复合右美托咪定（DEX）在心脏手术中的麻醉效果及对患者血流动力学的影响。方法：选取我院
2013 年12 月至2015年9 月行心脏手术的100 例患者，按随机数字表法分为两组麻醉I组和麻醉II组各50 例。麻醉II组患者以
REM复合DEX进行麻醉；麻醉I组患者以REM 行麻醉。比较不同麻醉方式的麻醉效果及对血流动力学的影响。结果：麻醉II组
患者手术不同时间点动脉压、心率、血氧饱和度变化不明显，（P＞0.05）。麻醉I组患者插管即刻动脉压、心率、血氧饱和度下降显
著，经t检验对比后有统计学意义（P＜0.05）。麻醉II组Ramsay评分明显高于麻醉I组，经t检验对比后有统计学意义（P＜0.05）。
两组患者拔管、苏醒、恢复呼吸时间相近，无显著差异（P＞0.05）。麻醉II组麻醉优良率明显高于麻醉I 组，经x2检验对比后有统
计学意义（P＜0.05）。结论：REM复合DEX 在心脏手术中的麻醉效果确切，可维持患者血流动力学的平稳，提高镇静效果。同时不
影响其拔管、苏醒和呼吸恢复，值得推广。 |
| 英文摘要: |
| Objective:To investigate the anesthetic effect of remifentanil(REM) combined with dexmedetomidine(DEX) in cardiac
surgery and its influence on hemodynamics.Methods:100 patients underwent cardiac surgery in our hospital from December 2013 to
September 2015, who were divided into anesthetic group I and anesthetic group II by randomnumber table method, with 50 cases in each
group.Anesthetic group II was treated with REM combined with DEX,while the anesthetic group I was treated with REM.Compared the
anesthetic effect of different anesthetic methods and the influence on hemodynamics.Results:The arterial pressure, heart rate and blood
oxygen saturation were not changed significantly at different time points in anesthetic group II, the t test showed that the difference was
not statistically significant(P>0.05). Above indexes in anesthetic group I at intubation immediately were significantly decreased, the t test
showed that the difference was statistically significant (P<0.05). Ramsay score in anesthetic group II was significantly higher than anesthetic
group I, the t test showed that the difference was statistically significant (P<0.05). The extubation, analepsia, recovery of breathing
time in two groups were closed, the difference was not statistically significant(P>0.05). The superior rate of anesthesia in anesthetic group
II was significantly higher than anesthetic group I, the X2 test showed that the difference was statistically significant (P<0.05).Conclusion:The anesthetic effect of REMcombined with DEX is obvious in cardiac surgery, which can maintain the stability of the hemodynamics,
improve the sedative effect, at the same time, it does not affect the extubation, analepsia, recovery of breathing,it is worth promoting. |
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