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目的：对比ApexitPlus 氢氧化钙糊剂和氧化锌碘仿糊剂结合牙胶尖在慢性牙髓炎患者根管治疗一次法中的临床应用价值差异。方法：选取110 例（124 颗）慢性牙髓炎患者为研究对象，在征询患者同意的前提下采用随机数字表法将其分成ApexitPlus 氢氧化钙糊剂组（A 组，n=55，63 颗）和氧化锌碘仿糊剂组（B 组，n=55，61 颗）两组。两组患者均予以一次性根充疗法，行为期12-24 个月随访，比对其术后根管填充效果及临床疗效差异，记录治疗前后疼痛评分及睡眠质量评分差异，分析术后急症反应发生情况。结果：①两组患者在根管填充效果对比上均无统计学意义（P>0.05）；其中A组患者术后3 个月内治疗成功率为100.0 %，显著高于B 组的91.8%（P<0.05）；B 组患者随访第24 个月时治疗成功率为83.6 %，显著低于A组的96.8 %（P<0.05）；②治疗后，两组患者视觉模拟评分法(VAS)及匹兹堡睡眠质量指数（PSQI）等治疗指标均较治疗前显著降低，其中A 组降幅大于B 组（P<0.05）； ③ A 组患者术后7 d内急症反应发生率为10.9 %，显著低于B组的38.2 %（P<0.05）。结论：对慢性牙髓炎患者以ApexitPlus 氢氧化钙糊剂+牙胶尖为填充材料行一次性根充治疗，疗效确切且根充效果良好，可有效降低其术后急症反应发生风险，对提高治疗效果、改善患者预后质量等方面具有积极影响，值得临床推广。

英文摘要:

Objective:To compare the differences in clinical application value ofApexitPlus calciumhydroxide paste and zinc oxide iodoform paste combined with gutta percha point in the one-visit root canal therapy for treating patients with chronic pulpitis.Methods:110 patients (124 teeth) with chronic pulpitis were selected as the research objects. On the premise of patients' agreement, the patients were divided into the ApexitPlus calcium hydroxide paste group (group A, n=55, 63 teeth) and the zinc oxide iodoform paste group (group B, n = 55, 61 teeth) of two groups according to the random number table method. The two groups of patients were given one-visit root canal therapy, with a period of 12 to 24 months of follow-up in behavior phase. The effect of root canal filling after operation and the clinical curative effect were compared. The differences in pain scores and sleep quality scores before and after the treatment were recorded and the incidence of postoperative emergency response was analyzed.Results:①There were no statistical significances in the effect of root canal filling between the two groups (P>0.05). The treatment success rate of group A in 3 months after operation (100.0%) was significantly higher than that of group B (91.8%) (P<0.05). The treatment success rate of group B at the 24th month of follow-up (83.6 %) was significantly lower than that of group A (96.8 %) (P<0.05); ②After the treatment, the visual analgesia score (VAS), Pittsburg sleep quality index (PSQI) and other treatment indexes of the two groups were significantly lower than those before the treatment and the decline in group A was greater than that in groupB (P<0.05); ③In 7d after operation, the occurrence rate of postoperative emergency response in groupA (10.9 % ) was significantly lower than that in groupB (38.2%) (P<0.05).Conclusion:To treat patients who have chronic pulpitis with ApexitPlus calcium hydroxide paste and gutta percha point as the filling materials for one-visit root canal therapy, the curative effect is exact and the root filling effect is good, which can effectively reduce the risk of postoperative emergency response and have a positive impact on improving the therapeutic effect, the prognosis and quality of life of patients. It is worth clinical promotion.

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