| 王坚 王锡阳 王科 刘子俊 郭时湘.椎体成形术和椎体后凸成形术治疗老年人骨质疏松性压缩性骨折的疗效比较[J].现代生物医学进展英文版,2016,16(28):5497-5501. |
| 椎体成形术和椎体后凸成形术治疗老年人骨质疏松性压缩性骨折的疗效比较 |
| Comparison of Percutaneous Vertebroplasty and Kyphoplasty in Treatment ofOsteoporotic Vertebral Compression Fractures in the Primary Hospital |
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| DOI： |
| 中文关键词: 骨质疏松 椎体骨折 经皮椎体成形术 经皮椎体后凸成形术 |
| 英文关键词: Osteoporosis Vertebral compression fracture Percutaneous vertebroplasty Percutaneous kyphoplasty |
| 基金项目:国家自然科学基金项目（81171736） |
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| 中文摘要: |
| 目的：比较经皮椎体成形术（percutaneous vertebroplasty，PVP）和经皮椎体后凸成形术（percutanous kyphoplasty，PKP）治疗骨
质疏松性压缩性骨折（Osteoporotic vertebral compression fracture，OVCF）的疗效。方法：回顾性分析2011 年5 月到2014年4 月我
院收治的老年骨质疏松性脊椎压缩性骨折患者共120 例124 椎，其中PVP 术66 例70 椎，PKP 术54 例54 椎。病椎范围从T6 至
L5。比较两组病人术前1 天、术后第2 天椎体恢复高度，后凸角变化；术前1 天、术后第2 天、末次随访时间疼痛视觉模拟评分
（Visual analogue scale,VAS）；术前1 天、末次随访时间Oswestry功能障碍指数（Oswestry Dability Index,ODI），平均住院日(average
length of stay,ALOS)和住院费用。结果：随访3 ～35 个月，平均17.4 月，术后椎体高度恢复情况：PVP 组vs PKP组组间差异无显
著(8.05± 0.59 mmvs 7.44± 0.53 mm, P=0.440)。两组术后后凸角均变小（PVP组10.33，PKP 组9.96，P=0.731），两组间差异无显著
性；患者的VAS 评分( 术前PVP 组8.65± 0.14，PKP 组8.44± 0.15，P=0.750；术后PVP 组2.91± 0.12，PKP 组2.85± 0.13，P=0.443)
两组间差异无显著性；ODI术前、术后两组间比较差异无显著性；平均住院日两组间差异无显著性（P=0.854），平均住院费用差异
有显著性（P=0.000），PVP 术住院费用显著低于PKP 术。结论：两种手术方式临床疗效没有差异，但PVP 术住院费用显著低于
PKP 术，PVP术是基层医院老年人OVCF治疗的合适的治疗方式。 |
| 英文摘要: |
| Objective:To compare the efficacy of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the
treatment of osteoporotic vertebral compression fracture (OVCF).Methods:120 cases (124 vertebrae) diagnosed OVCF from May 2011
to April 2014 were retrospective reviewed, of which 66 cases (70 vertebrae) were treated with PVP and 54 cases (54 vertebrae) were
treated with PKP. The diseased vertebral ranged from T6 to L5. The vertebral height, the changes of Cobb' angle, the visual analogue
scale (VAS), and the oswestry dability index (ODI) was recorded and compared before and after operation between two groups. pr The
average length of stay (ALOS), and the hospital costs in the two groups were compared.Results:The follow up periods were 3-35
months. The postoperative Cobb' angle in two groups became smaller and the change was no significant difference between two groups
(P>0.05). The VAS,ODI (pre- and post-operation), ALOS in the two groups had no significant difference (P=0.854). The average hospital
cost in PVP group was significantly lower than that in PKP group (P=0.000＜0.05).Conclusion:The clinical curative efficacy of PVP
and PKP was similar in treatment of OVCF, but the cost of PVP was significantly lower than that of PKP, indicating that PVP is the
appropriate treatment for elderly patients with OVCF in the primary hospital. |
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