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郭晓敏 陈瑞莉 李鹏 陈博.MCA供血区急性脑梗死SWI图像与脑血管反应性的相关性[J].现代生物医学进展英文版,2016,16(28):5479-5482.
MCA供血区急性脑梗死SWI图像与脑血管反应性的相关性
Relationship between Susceptibility-weighted Imaging and CerebrovascularReactivity in Patients with Acute Cerebral Infarction in MCA Territory
  
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中文关键词: 脑缺血  卒中  大脑中动脉  脑静脉  磁共振成像
英文关键词: Brain Ischemia  Stroke  Middle cerebral artery  Cerebral veins  Magnetic Resonance Imaging
基金项目:陕西省人民医院神内科基金项目(Z33)
Author NameAffiliation
郭晓敏 陈瑞莉 李鹏 陈博 陕西省人民医院神经脑科病院陕西省人民医院神经外科 
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中文摘要:
      目的:分析大脑中动脉供血区(MCA)急性脑梗死患者的磁敏感加权成像(SWI),探讨梗死侧侧脑室旁深部髓质静脉(DMV) 数量与脑血管反应性(CVR)的相关性。方法:回顾性纳入首次发生患侧MCA 供血区卒中患者109 例,并已完成TCD CO2负荷实 验和SWI等检查。根据SWI图像将DMV 数量分为3 级,<5条为1 级;5-10 条为2 级;>10 条为3 级,分析DMV 分级与CVR的 关系。结果:根据排除标准共纳入MCA供血区急性脑梗死患者53 例,DMV 1级、2级和3级分别有29、18、6 例患者,MCA 平均 CVR 为0.40± 0.18。DMV 1级CVR 为(0.45± 0.22)、2 级为(0.35± 0.15)和3 级为(0.20± 0.11),3 组患者间CVR 存在明显差异 (P<0.05),且DMV 3级组较DMV 1级组、2级组显著降低(P<0.05);Spearman 相关分析表明,DMV 分级与CVR 间存在明显的负 性相关关系(P<0.001)。结论:MCA 供血区脑梗死患者DMV 分级与患侧MCA CVR呈负相关关系。
英文摘要:
      Objective:To analyze the susceptibility weighted imaging (SWI) in patients with acute cerebral infarction in middle cerebral artery (MCA) territory, and to explore the relationship between the number of deep medullary vein (DMV) and cerebrovascular reactivity (CVR) in the lateral ventricles of the cerebral infarction.Methods:109 patients with stroke for the first time from the affected side of MCA were selected, and their CO2 TCD challenge test and SWI examination were completed. According to the numbers of DMV on SWI, they were classified into 3 grades: grade 1: DMV <5; grade 2: DMV 5-10; grade 3: DMV>10. The relationship between DMV classification and CVR were analyzed.Results:According to the exclusion criteria, a total of 53 patients with acute cerebral infarction in MCA territory were included. There were 29 patients in DMV grade 1, 18 in DMV grade 2 and 6 in DMV grade 3. The mean CVR of MCA was (0.40± 0.18). The CVR was (0.45 ± 0.22) in DMV grade 1, (0.35 ± 0.15) in DMV grade 2 and (0.20 ± 0.11) in DMV grade 3, and there was a significant difference between three groups (P<0.05). Moreover, the CVR in DMV grade 3 was significantly lower than in DMV grade 1 and 2 groups (P<0.05). Spearman correlation analysis showed that there was a significant negative correlation between DMV classification and CVR (P<0.001)Conclusion:The DMV grade in patients with cerebral infarction in MCA territory was negatively correlated with the CVR in the affected side.
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