| 朱艳 张慧 贺晓丹 张剑 马波江 张志斌 刘哲.灯盏细辛口服液对急性冠状动脉综合征患者外周血C-反应蛋白、MCP-1
和MMP-9 水平的影响[J].现代生物医学进展英文版,2016,16(27):5357-5360. |
| 灯盏细辛口服液对急性冠状动脉综合征患者外周血C-反应蛋白、MCP-1
和MMP-9 水平的影响 |
| Effect of Erigeron Breviscapus Oral Liquid on the C- reactive Protein, MCP-1and MMP-9 Levels in Peripheral Blood by in Patients with Acute CoronarySyndrome |
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| DOI： |
| 中文关键词: 灯盏细辛口服液 急性冠状动脉综合征 1-甲基环丙烯 MMP-9 C- 反应蛋白 |
| 英文关键词: Erigeron breviscapus oral liquid Acute coronary syndrome MCP-1 MMP-9 C- reactive protein |
| 基金项目:陕西省自然科学基础研究计划项目(2012JM4004) |
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| 中文摘要: |
| 目的：探讨灯盏细辛口服液对急性冠状动脉综合征患者外周血C-反应蛋白、1- 甲基环丙烯和9-基质金属蛋白酶水平的影
响。方法：选取我院心内科已确诊为急性冠状动脉综合征的患者110 例，随机分为实验组和对照组，对照组行常规药物治疗，实验
组在对照组的基础上口服灯盏细辛口服液。比较两组患者治疗前后外周血C- 反应蛋白变化情况及MCP-1 及MMP-9 水平及临
床疗效。结果：与治疗前相比，两组患者治疗后MCP-1、MMP-9 及C- 反应蛋白水平降低(P<0.05)，与对照组相比，实验组患者
MCP-1、MMP-9 及C- 反应蛋白较低(P<0.05)；与对照组相比，实验组总有效率较高(P<0.05)。结论：灯盏细辛口服液对急性冠状动
脉综合征患者具有较好的疗效，这可能与其降低外周血中C-反应蛋白、MMP-9和MCP-1 水平具有一定的关系。 |
| 英文摘要: |
| Objective:To investigate the effect of the C- reactive protein, MCP-1 and MMP-9 levels in peripheral blood by
erigeron breviscapus oral liquid in patients with acute coronary syndrome.Methods:110 patients with acute coronary syndrome from department
of Cardiology in our hospital were selected and randomly divided into the control group and the experiment group. The C- reactive
protein, MCP-1 and MMP-9 levels in peripheral blood were tested and compared before and after treatment.Results:Compared with
before treatment, the levels of MCP-1, MMP-9 and C- reactive protein were lower (P<0.05). Compared with the control group after treatment,
the levels of MCP-1, MMP-9 and C- reactive protein were lower(P<0.05), the total effective rate were higher(P<0.05).Conclusion:Erigeron breviscapus oral liquid can reduce the acute coronary artery syndrome in patients with peripheral blood C reactive protein,
MCP-1 and MMP-9 levels, of acute coronary artery comprehensive syndrome clinical treatment has important clinical significance. |
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