王莹 兰艳丽 王临轮 余开华 赵维 王天生.听性脑干反应在脑外伤后听力患者的早期诊断及预后中的意义[J].现代生物医学进展英文版,2016,16(27):5336-5339. |
听性脑干反应在脑外伤后听力患者的早期诊断及预后中的意义 |
ABR in Early Diagnosis and Its Prognosis of Patients with Dysaudia after Craniocerebral Trauma |
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DOI: |
中文关键词: 脑外伤 听性脑干反应 听力损伤 主波 潜伏期 |
英文关键词: Brain injury ABR Hearing loss Main wave Incubation period |
基金项目:四川省教育厅科学技术研究项目(2011658);湖南省自然科学基金项目(12JJ4079) |
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中文摘要: |
目的:探讨脑外伤后伴发听力损伤的患者听性脑干反应的特点及其和预后的相关性。方法:纳入颅脑外伤伴发听力障碍的
患者50 例,其中男34 例,女16 例,为观察组,选健康正常成年人50 例为对照组,其中男30 例,女20 例。对观察组受伤后2周内
及6 个月后进行听性脑干反应检查,对比分析两组患者听性脑干反应波特点及其和预后的相关性。结果:正常人听觉阈值的95%
置信区间是[10.24-19.33] dBHL。观察组和对照组的听觉阈值分别为52.24± 21.75 (dBnHL)、11.36± 3.02(dBnHL),差异有统计学
意义(p<0.05)。对照组主波Ⅰ、Ⅲ、Ⅴ出现率为100 %,观察组的出现率分别为78.00%、66.00%、88.00%,差异有统计学意义(P<
0.05)。病例组和对照组相比,Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ潜伏期均延长,差异存在统计学意义(P< 0.05)。预后良好组患者受伤2 周内和6 个月
后Ⅰ、Ⅲ、Ⅴ出现率明显增加,潜伏期缩小,差异有统计学意义(P<0.05)。而无改善组患者Ⅰ、Ⅲ、Ⅴ出现率略有增加,潜伏期缩小不
明显,差异无统计学意义(P>0.05)。结论:脑外伤患者听性脑干反应主波Ⅰ、Ⅲ、Ⅴ缺失,潜伏期缩小,若此种变化持续不改善,预示
着听力损伤预后较差。 |
英文摘要: |
Objective:To investigate the characteristics of auditory brainstemresponses (ABR) in brain injury patients with hearing
loss and analyze its correlation with prognosis.Methods:Included in this research were 50 patients of craniocerebral trauma with
hearing impairment, 34 males and 16 females, as observation group. 50 cases of healthy normal adults were included as control group at
the same time, including 30 cases of male, 20 cases of female. ABR was conducted in patients in the observation group at 2 weeks and 6
months after injury. Analyze and compare the brainstemresponse potter point and its correlation with prognosis.Results:The 95%confidence
of normal human auditory threshold interval is [10.24~19.33] dBHL. Auditory threshold value of observation group and control
group were respectively 52.24± 21.75 (dBnHL) and 11.36± 3.02 (dBnHL), and the difference was statistically significant (p<0.05). The
appearing rates of the main waves Ⅰ, Ⅲ, Ⅴ were 100%in control group, and were 78.00%, 66.00%and 78.00%respectively in observation
group, and the difference was statistically significant (P<0.05). Compared to the control group, the Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ incubation period
was extended in the observation group, and there was statistical difference (P<0.05). The appearing rate of the wave of Ⅰ, Ⅲ, Ⅴ increased
significantly in the group of patients with good prognosis at 2 weeks and 6 months after injury, and incubation period was shortened,
and the difference was statistically significant (P<0.05). While in the group of patients without improvement, the appearing rate of
waves Ⅰ, Ⅲ, Ⅴ showed a slight increase, and the shrink of incubation period was not obvious (P>0.05).Conclusion:The main waves
Ⅰ, Ⅲ, Ⅴ were missing and the incubation period was shortened in patients with traumatic brain injuries. Such unimproved status would
indicate poor prognosis of hearing impairment. |
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