| 满文玲 温小斐 李威 郭欢庆 李任飞 杨坡△.部分脾动脉栓塞术治疗原发性肝癌合并脾功能亢进的临床疗效观察[J].现代生物医学进展英文版,2016,16(23):4571-4573. |
| 部分脾动脉栓塞术治疗原发性肝癌合并脾功能亢进的临床疗效观察 |
| Observation on the Clinical Efficiency of Partial Artery Embolization inTreating Primary Liver Cancer combined with Hypersplenism |
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| DOI： |
| 中文关键词: 部分脾栓塞术 原发性肝癌 脾功能亢进 临床疗效 安全性 |
| 英文关键词: PSE Hepatocellular carcinoma Hypersplenism |
| 基金项目:黑龙江省教育厅资助项目(11551284) |
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| 中文摘要: |
| 目的：探讨部分性脾动脉栓塞术(PSE)治疗原发性肝癌合并脾功能亢进的临床疗效及安全性。方法：选择2008 年5 月至
2013年4 月我科收治的160 例原发性肝癌合并有脾功亢进患者为研究对象，患者在行肝动脉化疗栓塞术(TACE) 的同时进行
PSE，PSE 栓塞面积在30%~60%之间，观察治疗后3 天、7 天、1 个月、3 个月、6 个月患者白细胞(WBC)计数和血小板(PLT)计数的
动态变化情况。结果：以外周血白细胞计数达到4.0~13× 109/L、血小板达计数到50× 109/L为治疗有效，160例患者术后3 个月时
外周血白细胞治疗有效为151 例(94.38%)，血小板治疗有效为155 例(96.88%)，术后6 个月时白细胞治疗有效136 例(85%)，血小
板治疗有效125 例(78.13%)。所有患者术后6 个月均未发生严重并发症。结论：PSE 联合TACE治疗原发性肝癌合并有脾功亢进
患者具有良好的疗效，且安全性较高。 |
| 英文摘要: |
| Objective:To investigate the clinical efficiency of partial splenic artery embolization in treating primary hepaticarcinoma
with hypersplenism.Methods:From Jan 2008 to Oct 2013, 160 cases of hepatocellular carcinoma with hypersplenism treated with
transcatheter artery chemoembolization(TACE) combined with partial splenic artery embolization(PSE). The embolism area of PSE was
30%~60%, the WBC and PLT count were observed before treatment and 3 d, 7 d, 1 M, 3 M, 6 M after embolization.Results:WBC
4.0~13× 109/L and PLT 50× 109/L were considered to be effective. On 3 months, 152 cases (94.38%) were effective in WBC and 155
cases (96.88%) in PLT. On 6 months, 136 cases (85%) were effective in WBC and 125 cases (78.13%) in PLT. No serious complication
was observed.Conclusion:PSE with TACE was safe and effective for hepatocellular carcinoma with hypersplenism. |
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