| 高寿艳 陈秋月 刘娜娜 岳英丽 窦晓丽.尿毒症维持性血液透析患者血清CRP与营养状态及感染的相关性[J].现代生物医学进展英文版,2016,16(23):4542-4544. |
| 尿毒症维持性血液透析患者血清CRP与营养状态及感染的相关性 |
| Uremia Patients with Maintenance Hemodialysis: Correlation between Serum CRP and Nutritional Status and Infection |
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| DOI： |
| 中文关键词: 尿毒症 维持性血液透析 血清CRP 营养状态 感染 |
| 英文关键词: Uremia Maintenance hemodialysis SerumCRP Nutritional status Infection |
| 基金项目:2013 年廊坊市科学技术研究与发展计划自筹经费项目（2013013009） |
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| 中文摘要: |
| 目的：探讨尿毒症维持性血液透析患者的血清C-反应蛋白（CRP）与营养状态及感染的相关关系。方法：按照是否发生感染
将2013 年2 月-2015 年8 月我院收治的238 例尿毒症维持性血液透析患者分为感染组（118 例）和非感染组（120 例），对两组患
者的血清CRP、营养状态相关指标进行比较，并分析CRP 水平与营养状态及感染的相关性。结果：感染组的体质量指数（BMI）、白
蛋白、前白蛋白、转铁蛋白、血红蛋白水平低于非感染组，重组人促红细胞生成素、血清CRP 水平高于非感染组，肱三头肌皮褶厚
度低于非感染组，差异均有统计学意义（P<0.05）。经Pearson 积矩相关分析，血清CRP 与BMI、白蛋白、前白蛋白、转铁蛋白、血红
蛋白呈负相关关系（r=-0.81、-0.93、-0.85、-0.79、-0.91），差异有统计学意义（P<0.05），血清CRP 与肱三头肌皮褶厚度（TSF）呈负相
关关系（r=-0.76，P<0.05），与重组人促红细胞生成素呈正相关关系（r=0.89，P<0.05）。结论：尿毒症维持性血液透析患者的血清CRP
水平可作为评估患者营养状态及感染的重要指标，具有重要的参考价值。 |
| 英文摘要: |
| Objective:To explore the correlation between serum C reactive protein (CRP) and nutritional status and infection in
uremia patients with maintenance hemodialysis.Methods:A total of 238 uremia patients with maintenance hemodialysis, who were
admitted to Langfang People's Hospital of Hebei Province fromFebruary 2013 to August 2015, were divided into infection group(118 patients)
and non-infection group (120 patients) according to whether occurred the infection. The serumCRP and relevant indexes of nutritional
status of patients in the two groups were compared,and the correlation between CRP and nutritional status and infection was analyzed.Results:The BMI, albumin, prealbumin, transferrin and haemoglobin levels in infection group were lower than those in non-infection
group, but the erythropoietin and serum CRP were higher than those in non-infection group,and the triceps skinfold thickfold was
lower than that in non-infection group, the differences were statistically significant (P<0.05). The Pearson product monment correlation
analysis showed that there was a negative correlation between CRP and BMI, albumin, prealbumin, transferrin and haemoglobin levels
(r=-0.81,-0.93,-0.85,-0.79,-0.91), the difference was statistically significant (P<0.05). There was a negative correlation between CRP and
triceps skinfold thickfold(r=-0.76, P<0.05), and there was a positive correlation between CRP and erythropoietin(r=0.89, P<0.05).Conclusion:The serum CRP of uremia patients with maintenance hemodialysis can be used as an important index to evaluate the nutritional
status and infection, which has an important reference value. |
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