| 杨亚茹 何文 阎进晓 钱洲 赵晓燕.布地奈德联合高渗盐水治疗毛细管支气管炎临床疗效研究[J].现代生物医学进展英文版,2016,16(23):4523-4525. |
| 布地奈德联合高渗盐水治疗毛细管支气管炎临床疗效研究 |
| Clinical Efficacy of Budesonide Combined Hypertonic Saline in Treatment ofCapillary Bronchitis |
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| 中文关键词: 雾化吸入 布地奈德 高渗盐水 毛细管支气管炎 |
| 英文关键词: Atomization inhalation Budesonide Hypertonic saline Capillary bronchitis |
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| 中文摘要: |
| 目的：探讨雾化吸入布地奈德联合高渗盐水治疗毛细管支气管炎临床效果。方法：选取2012 年10 到2014 年10 月100 例
毛细管支气管炎患者为研究对象，分成2 组，有明确细菌感染者，给予敏感抗生素头孢呋辛钠80 mg/kg，每日2 次，或美洛西林钠
80-100 mg/kg，每日2 次，此外给予对症治疗，如止咳化痰（羚贝止咳糖浆）。对照组50 例，予高渗盐水治疗，吸入0.9 %氯化钠注射
液2 mL 和吸入用布地奈德混悬液（普米克令舒）1 mg/次混合液，观察50 例，吸入3%氯化钠注射液2 mL配合吸入用布地奈德混
悬液（普米克令舒）1 mg/次，观察治疗后相关指标变化情况。结果：疗效观察，对照组显效率62 %，总有效率82 %，观察组显效率
78 %，总有效率92 %，两组比较差异有统计学意义（P<0.05）；肺功能上，两组治疗前后在FEV1、FVC、PEF、FVC/ FEV1 对比差异
明显（P均<0.05），组间对比差异明显（P<0.05）；两组治疗后在咳嗽、哮鸣音、胸闷气短、住院时间比较差异有统计学意义（P均<0.
05）。结论：雾化吸入布地奈德联合高渗盐水治疗毛细管支气管炎临床效果显著。 |
| 英文摘要: |
| Objective:To investigate the clinical efficacy of atomization inhalation budesonide combined hypertonic saline in
treatment of capillary bronchitis, in order to improve the clinical diagnosis level.Methods:100 cases with capillary bronchitis from Oct.
2012 to Oct. 2014 were chosen, who were divided into two groups. The patients who have clear bacteria infection were given cefuroxime
sodium 80 mg/kg 2 times daily, or mezlocillin sodium 80-100 mg/kg 2 times daily, in addition giving symptomatic treatment such as
cough phlegm (Lingbei Cough Syrup). The control group were 50 cases, who were given hypertonic saline treatment (inhalation of 0.9%
sodium chloride injection 2 mL and inhalation budesonide suspension liquid mixture 1 mg/time), the observation group were 50 cases,
whowere given atomization inhalation budesonide treatment (inhalation of 3% sodium chloride injection 2 mL and inhalation budesonide
suspension liquid mixture 1 mg/time), the relevant indicators of two groups were observed.Results:The significant efficacy of control
group was 62%, the total efficacy was 82%; the observation group was 78%and 92%, which had significant differences(P<0.05). The
FEV1, FVC, PEF, FVC/ FEV1 of two groups in lung function had significant differences(P<0.05). The two groups after treatment had obviously
significant differences (P<0.05). The coughing, wheezing sound, chest condition, hospital stays of two groups after treatment had
significant differences (P<0.05).Conclusion:The atomization inhalation budesonide combined hypertonic saline in treatment of capillary
bronchitis had remarkable clinical efficacy (P<0.05). |
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