| Objective:To explore the efficacy of bifid triple viable capsule combined with nutritional support in treatment of severe
acute pancreatitis.Methods:A total of 90 patients with severe acute pancreatitis, who were treated in Affiliated Hospital of School of
Medicine of Shanghai Jiaotong University fromJanuary 2014 to June 2015, were chosen as subjects and randomly divided into treatment
group(n=45) and control group (n=45). The control group was treated with nutritional support on the basis of conventional treatment, and
treatment group, with bifid triple viable capsule on the basis of control group's therapy. The C reactive protein, interleukin-8, tumor
necrosis factor, leucocyte count, amylase, lipase and lactate dehydrogenase of veinal blood of the patients in the two groups were detected
before and after treatment, and the treatment effect and gastrointestinal function were scored.Results:The total effective rate(95.56%) of
treatment group was significantly higher than that(80.00%) of control group, the difference was statistically significant(P<0.05). After 14d
of treatment, the levels ofC reactive protein, interleukin-8, tumor necrosis factor, leucocyte count, amylase, lipase and lactate dehydrogenase
in the two groups were all decrease, and the decrease in the treatment group was significantly greater than that in the control group,
the differences were statistically significant (P<0.05). The gastrointestinal function scores of two groups after treatment were lower than
before treatment,and the gastrointestinal function score of treatment group was significantly better than that of control group, the difference
was statistically significant (P<0.05).Conclusion:Bifid triple viable capsule combined with nutritional support in the treatment of
patients with severe acute pancreatitis can reduce the blood indexes of patients and enhance the gastrointestinal function, with good clinical
efficacy, which is worthy of clinical application. |
