| 孙晓霞 张兆波 张玉枝 张金铎 赵丹娜.血清β-HCG, hsCRP 及CRP检测对胎膜早破宫内感染的诊断价值[J].现代生物医学进展英文版,2016,16(22):4363-4366. |
| 血清β-HCG, hsCRP 及CRP检测对胎膜早破宫内感染的诊断价值 |
| Predictive Value of Serum β-HCG, hsCRP and CRP Levels on IntrauterineInfection of Pregnant Women with Premature Rupture of Membranes |
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| DOI： |
| 中文关键词: β-HCG hsCRP CRP 胎膜早破 宫内感染 |
| 英文关键词: β-HCG hsCRP CRP Premature rupture of membranes Intrauterine infection |
| 基金项目:教育部"新世纪优秀人才支持计划" 项目(NCET 11-11023) |
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| 中文摘要: |
| 目的：分析血清β-HCG，hsCRP 及CRP 检测对胎膜早破产妇宫内感染的诊断价值。方法：选择2013 年8 月-2015 年8 月我
院收治的胎膜早破患者61例作为研究组，另选择同期在我院行剖宫产手术的55 例患者作为对照组。检测并比较两组患者血清
β-HCG，hsCRP及CRP 水平，分析其水平变化用于诊断胎膜早破产妇发生宫内感染的敏感性及特异性。结果：研究组患者血清
β-HCG，hsCRP及CRP 水平均显著高于对照组，差异具有统计学意义（P＜0.05）；研究组患者宫内感染的发生率高于对照组，差异
具有统计学意义（P＜0.05）；重度宫内感染患者血清β-HCG，hsCRP 及CRP水平显著高于中度及轻度宫内感染者，差异具有统计
学意义（P<0.05）；中度宫内感染患者血清β-HCG，hsCRP及CRP水平高于轻度宫内感染者，差异具有统计学意义（P＜0.05）；
β-HCG，hsCRP及CRP 三项指标联合检测用于诊断胎膜早破产妇宫内感染的敏感性及特异性均高于任意一项指标单独检测的敏
感性及特异性，差异均具有统计学意义（P＜0. 05）。结论：胎膜早破产妇血清β-HCG，hsCRP及CRP水平联合检测用于预测宫内感
染的发生具有较高的灵敏性及特异性。 |
| 英文摘要: |
| Objective:To explore the predictive value of serum β-HCG, hsCRP and CRP levels on intrauterine infection of
pregnant women with premature rupture of membranes.Methods:61 patients with fetal membrane who were treated in our hospital from
August 2013 to August 2015 were selected as the study group and another 55 cases who had taken the cesarean section at the same time
in our hospital were chosen to be the control group. Then the serum levels of β-HCG, hsCRP and CRP in the two groups were detected
and compared, and the sensitivity and specificity of β-HCG, hsCRP and CRP on the diagnosis of intrauterine infection were analyzed.Results:The intrauterine infection rate in the study group was higher than that of the control group, and the difference was statistically
significant (P<0.05). The serumlevels of β-HCG, hsCRP and CRP in the study group were significantly higher than those of the control
group, and the difference was statistically significant (P<0.05). The serum levels of β-HCG, hsCRP and CRP of patients with severe
intrauterine infection were significantly higher than those of the moderate intrauterine infection and the slight intrauterine infection, and
the difference was statistically significant (P<0.05); The serumlevels of β-HCG, hsCRP and CRP in patients with moderate intrauterine
infection were higher than those of the slight intrauterine infection, and the difference was statistically significant (P<0.05); The
sensitivity and specificity of the combination detection of serum β-HCG, hsCRP and CRP levels were significantly higher than that of the
single index detection (P<0.05).Conclusion:The combination detection of serum levels of β-HCG, hsCRP and CRP has high sensitivity
and specificity on the prediction of the intrauterine infection of pregnant women with premature rupture of membranes. |
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