| Objective:To compare the clinical effect of triptorelin acetate and megestrol acetate tablets in the treatment of
idiopathic central precocious puberty.Methods:select our hospital since 2014 February 2015 during February were idiopathic central
precocious puberty in 92 cases of children, According to the random number table method, they were divided into 2 groups, 46 cases of
children only accept megestrol acetate tablets in the treatment (control group), 46 patients received triptorelin acetate treatment
(observation group). After 6 months treatment, compared the growth index and hormone level changes and statistical the adverse reaction
between two groups.Results:After treatment, the weight, height,growth rate,prediction of height, BA/CA growth index of observation
group was better than that of the control group (P<0.05); compared with before treatment, the E2, LH and FSH levels of two groups had
improved significantly after treatment(P<0.05); and the E2, LH and FSH levels of observation group was better than that of control group
(P<0.05); No obvious adverse reactions were found in the two groups.Conclusion:Comparing with megestrol acetate tablets, the clinical
effect of triptorelin acetate in the treatment of idiopathic central precocious puberty in children was more better, delay the maturation of
bone age of children, reduce the level of sex hormone, which has good application value in clinical. |
