| 付山 袁磊 张宇峰 杨建志 吴斌斌.丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用[J].现代生物医学进展英文版,2016,16(22):4325-4328. |
| 丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用 |
| The Effects of Continuous Infusion of Propofol and Etomidate Mixture inPainless Gastroscopy Anesthesia |
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| DOI： |
| 中文关键词: 丙泊酚 依托咪酯 无痛胃肠镜 麻醉 |
| 英文关键词: Propofol Etomidate Painless gastroscopy Anesthesia |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨丙泊酚和依托咪酯混合液持续泵注在无痛胃肠镜麻醉中的应用效果。方法：2013 年9 月到2015年2 月选择在我
院进行无痛胃肠镜检查患者120 例，根据随机数字表法分为治疗组60 例与对照组60 例，对照组给予丙泊酚辅助持续泵注麻醉，
治疗组给予丙泊酚和依托咪酯混合液辅助持续泵注麻醉。结果：所有患者都完成检查，两组MAP与HR 值在给药后2 min 与给药
前比较差异都有统计学意义(P<0.05)，在组间相比较无显著性差异(P>0.05)，其余时间点的上述值在组内与组间比较均无显著性
差异(P>0.05)。治疗组的诱导时间与离院时间都明显少于对照组(P<0.05)，对比两组的检查时间及苏醒时间，无显著性差异(P>0.
05)。治疗组检查后1 天内出现的恶心、呕吐、头晕等并发症发生情况明显少于对照组(P<0.05)。结论：丙泊酚和依托咪酯混合液持
续泵注在无痛胃肠镜麻醉中的应用对于患者的血流动力学影响小，能促进麻醉效果的提高，减少不良反应的发生，值得推广应用。 |
| 英文摘要: |
| Objective:To investigate the effects of continuous Infusion of propofol and etomidate mixture in painless gastroscopy
anesthesia.Methods:120 patients who were treated with painless, selected gastrointestinal endoscopy were collected From September
2012 to February 2015 in our hospital and were equally divided into the treatment group of 60 patients and the control group of 60
patients. The patients in control group were received propofol auxiliary continuous infusion anesthesia, and the patients of the treatment
group were received propofol and etomidate mixture assisted continuous infusion anesthesia.Results:All patients were completed the
examination, The MAP and HR values at 2 min after the administration in two groups compared with before administration were
statistically significant differences (P <0.05), but no difference was detectable between two groups. The above values for the remaining
time in the group and between the two groups showed no significant difference (P> 0.05). The induction time and time away from the
hospital in the treatment group were significantly less than that of the control group (P <0.05), while the examination time and wake time
were no statistically significant between two groups (P> 0.05). After treatment, the nausea, vomiting, dizziness, skin itching and other
complications in the treatment group were significantly less than those of the control group (P <0.05).Conclusion:Continuous infusion
anesthesia of propofol and etomidate mixture in painless gastroscopy has less hemodynamic effect, and it can promote the effect of
anesthesia and reduce the incidence of adverse reactions, worthy of promotion and applications in clinic. |
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