| 刘小燕 曹义娟△ 严晓南 祁玉娟 胡方方 杨亚茹.挥发性有机化合物(VOCs)对IVF实验室影响的研究进展[J].现代生物医学进展英文版,2016,16(21):4181-4184. |
| 挥发性有机化合物(VOCs)对IVF实验室影响的研究进展 |
| Research Progress of the Effect of VOCs on IVF Laboratory |
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| DOI： |
| 中文关键词: 挥发性有机化合物 配子- 胚胎发育 体外受精-胚胎移植 |
| 英文关键词: VOCs Gamete-embryo development In vitro fertilization-embryo transfer |
| 基金项目:：国家自然科学基金项目（81571405）；徐州中心医院博士（硕士）创新团队科技项目（xzs2012079） |
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| 中文摘要: |
| 体外受精-胚胎移植技术已成为当今治疗不育症的主要手段，为取得令人满意的临床妊娠率，体外受精(IVF)实验室的空气
质量控制成为生殖助孕工作者关注的重点。胚胎培养室的挥发性有机化合物(volatile organic compounds，VOCs)含量对配子- 胚
胎发育的影响至关重要，体外胚胎对VOCs的耐受能力差，其含量超过一定界限时则会对配子和胚胎造成影响。本文概述了IVF
实验室VOCs的来源，VOCs的生殖毒性，VOCs的测定方法以及胚胎培养室内VOCs 的控制途径等，旨在更严格的进行IVF实验
室的空气质量控制，尽可能杜绝VOCs的污染，提高IVF的成功率。 |
| 英文摘要: |
| In vitro fertilization and embryo transfer procedures have become a useful technique for treating in fertility. The major
concern of an IVF laboratory is the air quality control which can improve the high pregnancy rate. The effect of volatile organic compounds
(VOCs) is vital important to the gamete-embryo development in the embryo culture room. The tolerance ability of in vitro embryo
is poor to VOCs, and it will affect the embryo and the embryo when its content is more than a certain limit. This paper summarizes the
sources of VOCs in the IVF laboratory, the reproductive toxicity of VOCs, the control ways of VOCs of the embryo culture room, etc.
The aim is to control IVF laboratory air quality more strictly, as far as possible to eliminate the pollution of VOCs, and improve the success
rate of IVF. |
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