| 李晓芳 李萍 郭卫卫 楚有良 张欣.重症急性胰腺炎患者并发感染的临床特征及相关危险因素分析[J].现代生物医学进展英文版,2016,16(19):3700-3702. |
| 重症急性胰腺炎患者并发感染的临床特征及相关危险因素分析 |
| Clinical Feature and Risk Factors of Severe Acute Pancreatitis Complicated with Infection |
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| DOI： |
| 中文关键词: 重症急性胰腺炎 感染 危险因素 |
| 英文关键词: Severe acute pancreatitis Infection Risk factor |
| 基金项目: |
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| 中文摘要: |
| 目的：分析重症急性胰腺炎（SAP）患者并发感染的临床特征及感染的相关危险因素。方法：选择我院2009 年1 月至2014 年
1 月收治的SAP 患者152 例，所有患者入院后，根据有无发生并发感染分为感染组（n=48）和非感染组（n=105），详细记录两组临
床资料，并对SAP 患者并发感染的相关危险因素进行多因素回归分析。结果：152 例SAP 患者中有48例发生并发感染，并发感染
率为31.58%，对感染组患者标本进行分析，检出病原菌58 株，以肠杆菌属为主，其中阴沟肠杆菌最多，占比22.41%。经单因素及
多因素回归分析显示年龄≥ 60 岁、器官衰竭个数增加、禁食时间延长是SAP并发感染的独立危险因素（P<0.05）。结论：内源性感
染是SAP 患者并发感染的主要原因，且临床诊治中应针对SAP 并发感染的独立危险因素，及早给予必要的干预，降低SAP患者
并发感染的风险。 |
| 英文摘要: |
| Objective:To explore the clinical feature and risk factors of patients with severe acute pancreatitis (SAP) complicated
with infection.Methods:A total of 152 patients with SAP, who were admitted to Xi'an Central Hospital from January 2009 to January
2014,were selected and divided into infection group(n=48) and non-infection group(n=105) according the status of infection. The clinical
date of the two groups were recorded in detail, The risk factors of patients with SAP complicated with infection were dealt with by multivariate
regression analysis.Results:Among the 152 patients with SAP, there were 48 patients complicated with infection, accounting for
31.58%; the analysis of the specimens of the infection group showed that there were 58 pathogenic bacterias, among which, the enterobacter
took the major part, and the enterobacter cloacae was the most,accounting for 22.41%. The univariate analysis and multivariate
regression analysis showed that ≥ 60 years old, extended fasting time and the increase of number of organ failure were the independent
risk factors of SAP complicated with infection(P<0.05).Conclusion:Endogenous infection is the major reason of patients with SAP complicated
with infection, so necessary intervention should be given as early as possible in clinical diagnosis and treatment,regarding to its
risk factors, in order to reduce the risk of occurrence of infection. |
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