| 柳骥戎 蒋丽 胡力 黄江华 李云龙.AECOPD患者NPPV不同压力支持水平对腹内压力的影响[J].现代生物医学进展英文版,2016,16(15):2965-2968. |
| AECOPD患者NPPV不同压力支持水平对腹内压力的影响 |
| Effect of NPPV with Different Pressure Support Level on the Intra-abdominalPressure in Patients with AECOPD |
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| DOI： |
| 中文关键词: AECOPD NPPV IPAP 腹内压 |
| 英文关键词: AECOPD NPPV IPAP Intra-abdominal pressure |
| 基金项目:四川省卫生厅科研课题(100067) |
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| 中文摘要: |
| 目的：探讨慢性阻塞性肺病急性加重期（AECOPD）患者无创正压通气（NPPV）不同压力支持水平对腹内压力的影响。方法：
收集我院收治的AECOPD 患者150 例，随机分为A、B、C 三组，每组各50 例。给予所有患者无创机械通气，A、B、C 组患者分别给
予吸气相正压（IPAP）值为12 cmH2O、16 cmH2O、20 cmH2O，其他参数一致，通气治疗结束后，对所有患者的腹内压、不良反应发生
率、呼吸困难程度以及动脉血气水平进行检测并比较。结果：通气后，A、B、C 三组患者腹内压水平与通气前相比升高（P<0.05）；与
A、B组患者相比，C 组患者腹内压水平较高（P<0.05）；通气后，A、C 两组患者的不良反应发生率与B 组相比较高（P<0.05）；通气
后，B组患者呼吸困难评分与A、C组相比较高（P<0.05）。治疗后，三组患者的PaO2与通气前相比升高，PaCO2降低（P<0.05），与
A、C 组相比，B 组患者的PaO2水平较高，PaCO2较低（P<0.05）。结论：AECOPD患者通气后腹内压水平随NPPV 压力的升高而升
高；中等压力的无创正压通气能够改善AECOPD患者的呼吸困难以及动脉血气水平，降低不良反应发生率。 |
| 英文摘要: |
| Objective:To investigate the effect of noninvasive positive pressure ventilation（NPPV）in patients with different pressure
support level on the intra-abdominal pressure in patientswith acute exacerbation of chronic obstructive pulmonary disease（AECOPD）Methods:150 cases of AECOPD patients in our hospital were selected and randomly divided into group A, group B and group C, 50 cases
in each group. All the patients were given no invasive mechanical ventilation, and the patient in A, B, C groups were given inspiration
positive airway pressure(IPAP) value for 12 cmH2O, 16 cm H2O, 20 cmH2O, respectively, and the other parameters were the same. After
the end of the ventilation in the treatment, with the intra-abdominal pressure, incidence of adverse reactions, degree of dyspnea, and the
level of arterial blood gas were detected and compared among three groups.Results:Compared with before treatment, the intra-abdominal
pressure level were higher (P<0.05), and compared with the group A and the group B, the intra-abdominal pressure level in group C
were higher (P<0.05); Compared with the group B, the incidence of adverse reactions were higher and the dyspnea score was lower in
group A and groupC (P<0.05); Compared with before treatment, the PaO2 level was higher (P < 0.05), the PaCO2 level was lower (P <
0.05). Compared with A and C group, the PaO2 level of B group was higher and PaCO2was lower (P<0.05).Conclusion:The ventilated
intra-abdominal pressure level in patients with AECOPD is increased with increasing pressure of NPPV; mediumpressure of noninvasive
positive pressure ventilation can improve the dyspnea and arterial blood gas level, reduce the incidence of adverse reactions. |
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