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张超 韩洁 苏妍 崔颖 高慧.妊娠高血压患者血清PZ与hs-CRP水平检测的临床意义[J].现代生物医学进展英文版,2016,16(14):2766-2768.
妊娠高血压患者血清PZ与hs-CRP水平检测的临床意义
Clinical Significance of SerumPZ and hs-CRP Detection in Patients withPregnancy Induced Hypertension
  
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中文关键词: 妊娠高血压  血清蛋白Z  高敏C反应蛋白  检测  临床意义
英文关键词: Pregnancy induced hypertension  Serumprotein Z  hs-CRP  Detection  Clinical significance
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Author NameAffiliation
张超 韩洁 苏妍 崔颖 高慧 唐山市妇幼保健院内科 
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中文摘要:
      目的:探讨妊娠高血压患者血清蛋白Z(PZ)与高敏C反应蛋白(hs-CRP)水平检测的临床意义。方法:选择2011 年12 月到 2014 年12 月我院收治的120 例妊娠高血压患者作为实验组,同期选择100 例健康产妇作为对照组。检测所有研究对象的血清 PZ、hs-CRP 水平,分析比较不同血压、妊娠期下各组间血清PZ 与hs-CRP 的差别。结果:不同程度高血压组妊娠患者血清PZ、 hs-CRP水平差异具有显著性(P<0.05),随高血压程度加重,PZ水平下降、hs-CRP水平升高。实验组血清PZ水平随妊娠期发展逐 渐下降,且不同妊娠期血清PZ水平均明显低于对照组(P<0.05)。实验组血清hs-CRP水平随妊娠期发展逐渐上升,且不同妊娠期 血清hs-CRP 水平均明显高于对照组(P<0.05)。结论:血清PZ 水平降低和hs-CRP水平升高会导致孕妇血压升高,检测孕妇血清 PZ与hs-CRP 对预防和治疗妊娠高血压具有一定的临床意义。
英文摘要:
      Objective:To investigate the clinical significance of serum protein Z (PZ) and high sensitivity C reactive protein (hs-CRP) detection in patients with pregnancy induced hypertension.Methods:A total of 120 patients with pregnancy induced hypertension, who were admitted to Tangshan Maternal and Child Health Hospital from December 2011 to December 2014, were chosen as experiment group, and 100 contemporaneous healthy pregnancy women, as control group. The levels of serum PZ and hs-CRP in the two groups were detected, and the differences of serum PZ and hs-CRP in different blood pressures and gestation period were compared.Results:The serumPZ, hs-CRP levels of different blood pressures were significantly different(P<0.05), the serum PZ level decreased and hs-CRP level increased along with the increase of high blood pressure. The serum PZ level gradually decreased along with the development of gestation in experiment group, and it was lower than control group in each gestation period (P<0.05). The serum hs-CRP level gradually increased along with the development of gestation in experiment group,and it was higher than control group in each gestation period (P<0.05).Conclusion:The decrease of serum PZ and increase of serum hs-CRP can lead to high blood pressure among pregnancy women, which indicates that the serum PZ and hs-CRP detection plays an important role in the prevention and treatment of pregnancy induced hypertension.
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