| 胡建华 纪兆乐 杨亚丽 吕平 吴萌 李巍 李妍△.微循环阻力指数在心血管疾病中的应用[J].现代生物医学进展英文版,2016,16(13):2544-2547. |
| 微循环阻力指数在心血管疾病中的应用 |
| The Application of Index of Microcirculation Resistance in CardiovascularDisease |
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| DOI： |
| 中文关键词: 微循环阻力指数 围手术期心梗 微血管阻塞 |
| 英文关键词: Index of microcirculatory resistance Perioperative myocardial infarction Microvascular obstruction |
| 基金项目:国家自然科学基金项目（81170184） |
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| 中文摘要: |
| 随着医疗水平的发展，心血管疾病的诊断和治疗越来越规范和细致，不仅需要对心脏大血管进行评估，对微循环的评估也
是十分重要。微循环阻力指数（index of microcirculatory resistance,IMR）是2003 年由Fearon 医生提出的一种操作方便、能真实反
映微循环阻力的冠状动脉功能学定量评价指标。IMR 的可重复性好，且不受冠状动脉狭窄影响，在预测围手术期心梗、PCI术后微
血管阻塞、ST 段抬高性心肌梗死患者PCI预后，评价PCI辅助治疗手段的有效性，阐明应激性心肌病的发病机制以及评价心血管
药物的应用等方面具有重要意义。本文就IMR 的特点及临床应用做一综述。 |
| 英文摘要: |
| With improvements in healthcare, the diagnosis and treatment of cardiovascular diseases are becoming more and more
specific and detailed. Though it is critical to evaluate large blood vessels of heart, importance of microcirculation accessment is increasingly
valued. The concept of index of microcirculatory resistance (IMR) is raised by Dr. Fearon in 2003. IMR is a convenient quantitative
evaluation index that can actually reflect microcirculatory resistance, and not influenced by coronary artery stenosis. IMR has the advantage
of great reproducibility. This gives IMR a major value in predicting perioperative myocardial infarction, post-PCI microvascular
obstruction and prognosis of PCI patients with ST segment elevation myocardial infarction. Meanwhile, It also plays an important role in
evaluating auxiliary treatment of PCI, elucidating the pathogenesis of stress-induced cardiomyopathy and evaluating cardiovascular drugs.
This review discusses the features of IMR and its clinical applications. |
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